Introduction: Type 2 diabetes mellitus (DM2) affects health, social relationships,
physical fitness and functionality and quality of life. The aim of this study was to verify
whether variables related to functional capacity and glycemic control are predictors of
health-related quality of life (HRQOL) of DM2 patients in the city of Tocantinopolis
(TO). Methods: This is a cross-sectional and predictive study. The sample was required
for convenience. The sample included people with DM2, male and female, over 40 years
of age, which corresponded to 16% of the population of people with DM2 and
hypertension treated by the SUS in the city of Tocantinopolis, Tocantins, Brazil. All
answered a questionnaire containing sociodemographic information, diabetes
characteristics (time since diagnosis and chronic complications), physical activity,
smoking and/or alcohol use, sleep quality and health and a HRQL questionnaire specific
for DM2 (DQOL). Additionally, tests related to functional capacity (handgrip with a
dynamometer, sitting and standing, walking for six minutes), mobility (Timed up and go
Test (TUG)) and glycemic control (glycated hemoglobin - HbA1c) were performed. To
assess whether variables related to functional capacity and glycemic control predict
HRQoL, multiple linear regression was used. Analyzes were performed using the
statistical program R v. 3.6.3; for all analyses, the significance level for adjusting the
variables in the model at 20% was adopted. Results: the sample of respondents to the
questionnaire was 100 people with DM2, a subsample of 32 people performed all the tests
provided that were motivated by multiple linear regression. Not having DM2
complications (β = 7.9; p = 0.197) and having more strength in the upper (β = 2.5; p =
0.074) and lower limbs (β = 0.360; p = 0.2) were associated with Domain Satisfaction
with DM2 treatment. Lower limb strength (β = 2,104; p = 0.094) was associated with a
decrease in perceived impact on HRQOL. Flexibility also associated with the domain of
Social / Vocational Concerns. Having more lower limb strength (β = 1,932; p = 0.067)
and flexibility (β = 0.318; p = 0.142) was associated with better overall HRQoL. HbA1c
was inversely associated with general HRQOL (β = -1.307; p = 0.198), higher perception
of the Impact of the disease (β = -2.109; p = 0.070) and worse perception of Social /
vocational concerns (β = -0.955 ; p = 0.138). Conclusion: the predictive model with the
variables not having complications, strength of upper and lower limbs predicted 12%
satisfaction with the treatment in people with DM2. Glycated hemoglobin and lower limb
strength predict 14% of the perceived impact of DM2. The social/vocational concerns
domain had a lower predictive power (0.125%) influenced by the variables flexibility and
glycated hemoglobin. Finally, 12.5% of overall HRQOL is predicted by lower limb
strength, flexibility and glycated hemoglobin.
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