Bryophyllum pinnatum sp., a plant native to the African region of Madagascar but
widely disseminated in the subtropical region of Brazil, is popularly known as "saião,"
coirama, leaf of fortune and holy leaf. It is used in folk medicine due to its remarkable
analgesic, anti-inflammatory, and cicatrizing properties. However, the study of the chemical
profile of this medicinal species is relatively unexplored in the national scenario. In this
context, the present research stands out with the aim of contributing to the existing chemical
elucidation data in the literature. From fresh aerial parts, the objective was to qualitatively
determine the chemical compounds responsible for the therapeutic properties of the plant
species. The ethanolic extract of the leaves was obtained using a Soxhlet extractor, and after
partitioning with different solvents, GC-MS analysis was performed. The results obtained
reveal a significant chemical profile, including compounds with anticancer potential
(Jaceosidin), antimicrobial activity (Gondamid), action on the nervous system (Oleamide),
and various fatty acids (such as linoleic acid, palmitic acid, myristic acid) directly related to
the anti-inflammatory, anti-diabetic, and anti-hypertensive medicinal properties of the
species.
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