Artigo

Influence of tramadol on functional recovery of acute spinal cord injury in rats

Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a aminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn’t receive any...

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Autor principal: CHAVES, Rosa Helena de Figueiredo
Outros Autores: SOUZA, Celice Cordeiro de, FURLANETO, Ismari Perini, TEIXEIRA, Renan Kleber Costa, OLIVEIRA, Carolina Pinheiro de, RODRIGUES, Emanuelle de Matos, SANTOS, Daniel Arthur Santos dos, SILVA, Renata Cunha, PENHA, Nelson Elias Abrahão da, LIMA, Ana Rita de
Grau: Artigo
Idioma: eng
Publicado em: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2019
Assuntos:
Neuralgia
Pain
Analgesics
Rats
Acesso em linha: http://repositorio.ufpa.br/jspui/handle/2011/10796
http://dx.doi.org/10.1590/s0102-865020180120000006
id ir-2011-10796
recordtype dspace
spelling ir-2011-107962020-01-27T17:01:28Z Influence of tramadol on functional recovery of acute spinal cord injury in rats CHAVES, Rosa Helena de Figueiredo SOUZA, Celice Cordeiro de FURLANETO, Ismari Perini TEIXEIRA, Renan Kleber Costa OLIVEIRA, Carolina Pinheiro de RODRIGUES, Emanuelle de Matos SANTOS, Daniel Arthur Santos dos SILVA, Renata Cunha PENHA, Nelson Elias Abrahão da LIMA, Ana Rita de Neuralgia Pain Analgesics Rats Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a aminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn’t receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods. Results: There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group. Conclusion: The tramadol as an analgesic agent don’t influence on functional recovery of acute spinal cord injury in rats. FURLANETO, I. P. Universidade Federal do Pará 2019-03-27T18:15:43Z 2019-03-27T18:15:43Z 2018-12 Artigo de Periódico CHAVES, Rosa Helena de Figueiredo et al. Influence of tramadol on functional recovery of acute spinal cord injury in rats. Acta Cirúrgica Brasileira, São Paulo, v. 33, n. 12, p. 1087-1094,  Dec. 2018. DOI: http://dx.doi.org/10.1590/s0102-865020180120000006. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10796. Acesso em:. 1678-2674 http://repositorio.ufpa.br/jspui/handle/2011/10796 http://dx.doi.org/10.1590/s0102-865020180120000006 eng Acta Cirúrgica Brasileira Acesso Aberto application/pdf Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia Brasil SOBRADPEC http://ref.scielo.org/ncf8gn
institution Repositório Institucional - Universidade Federal do Pará
collection RI-UFPA
language eng
topic Neuralgia
Pain
Analgesics
Rats
spellingShingle Neuralgia
Pain
Analgesics
Rats
CHAVES, Rosa Helena de Figueiredo
Influence of tramadol on functional recovery of acute spinal cord injury in rats
topic_facet Neuralgia
Pain
Analgesics
Rats
description Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a aminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn’t receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods. Results: There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group. Conclusion: The tramadol as an analgesic agent don’t influence on functional recovery of acute spinal cord injury in rats.
format Artigo
author CHAVES, Rosa Helena de Figueiredo
author2 SOUZA, Celice Cordeiro de
FURLANETO, Ismari Perini
TEIXEIRA, Renan Kleber Costa
OLIVEIRA, Carolina Pinheiro de
RODRIGUES, Emanuelle de Matos
SANTOS, Daniel Arthur Santos dos
SILVA, Renata Cunha
PENHA, Nelson Elias Abrahão da
LIMA, Ana Rita de
author2Str SOUZA, Celice Cordeiro de
FURLANETO, Ismari Perini
TEIXEIRA, Renan Kleber Costa
OLIVEIRA, Carolina Pinheiro de
RODRIGUES, Emanuelle de Matos
SANTOS, Daniel Arthur Santos dos
SILVA, Renata Cunha
PENHA, Nelson Elias Abrahão da
LIMA, Ana Rita de
title Influence of tramadol on functional recovery of acute spinal cord injury in rats
title_short Influence of tramadol on functional recovery of acute spinal cord injury in rats
title_full Influence of tramadol on functional recovery of acute spinal cord injury in rats
title_fullStr Influence of tramadol on functional recovery of acute spinal cord injury in rats
title_full_unstemmed Influence of tramadol on functional recovery of acute spinal cord injury in rats
title_sort influence of tramadol on functional recovery of acute spinal cord injury in rats
publisher Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publishDate 2019
url http://repositorio.ufpa.br/jspui/handle/2011/10796
http://dx.doi.org/10.1590/s0102-865020180120000006
_version_ 1787149071291514880
score 11.687526

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