Complete genome sequence of Corynebacterium pseudotuberculosis biovar ovis strain P54B96 isolated from antelope in South Africa obtained by rapid next generation sequencing technology
The Actinobacteria, Corynebacterium pseudotuberculosis strain P54B96, a nonmotile, non sporulating and a mesophile bacterium, was isolated from liver, lung and mediastinal lymph node lesions in an antelope from South Africa. This strain is interesting in the sense that it has been found together...
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The Actinobacteria, Corynebacterium pseudotuberculosis strain P54B96, a nonmotile, non sporulating and a mesophile bacterium, was isolated from liver, lung and mediastinal lymph node
lesions in an antelope from South Africa. This strain is interesting in the sense that it has been
found together with non-tuberculous mycobacteria (NTMs) which could nevertheless play a role
in the lesion formation. In this work, we describe a set of features of C. pseudotuberculosis
P54B96, together with the details of the complete genome sequence and annotation. The genome
comprises of 2.34 Mbp long, single circular genome with 2,084 protein-coding genes, 12 rRNA,
49 tRNA and 62 pseudogenes and a G+C content of 52.19%. The analysis of the genome se quence provides means to better understanding the molecular and genetic basis of virulence of
this bacterium, enabling a detailed investigation of its pathogenesis. |