Draft genome sequences of two species of “difficult-to-identify” human-pathogenic corynebacteria: implications for better identification tests.
Non-diphtheriae Corynebacterium species have been increasingly recognized as the causative agents of infections in humans. Differential identification of these bacteria in the clinical microbiology laboratory by the most commonly used biochemical tests is challenging, and normally requires add...
| Autor principal: | PACHECO, Luis Gustavo Carvalho |
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| Outros Autores: | GUARALDI, Ana Luiza de Mattos, SANTOS, Carolina Silva, VERAS, Adonney Allan de Oliveira, GUIMARÃES, Luís Carlos, ABREU, Vinicius Augusto Carvalho de, PEREIRA, Felipe Luiz, SOARES, Siomar de Castro, DORELLA, Fernanda Alves, CARVALHO, Alex Fiorini de, LEAL, Carlos Augusto Gomes, FIGUEIREDO, Henrique Cesar Pereira, RAMOS, Juliana Nunes, VIEIRA, Verônica Viana, FARFOUR, Eric, GUISO, Nicole, HIRATA JÚNIOR, Raphael, AZEVEDO, Vasco Ariston de Carvalho, SILVA, Artur Luiz da Costa da, RAMOS, Rommel Thiago Juca |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
Ivyspring International Publisher
2023
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| Assuntos: | |
| Acesso em linha: |
https://repositorio.ufpa.br/jspui/handle/2011/15722 |
| Resumo: |
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Non-diphtheriae Corynebacterium species have been increasingly recognized as the causative agents
of infections in humans. Differential identification of these bacteria in the clinical microbiology
laboratory by the most commonly used biochemical tests is challenging, and normally requires
additional molecular methods. Herein, we present the annotated draft genome sequences of two
isolates of “difficult-to-identify” human-pathogenic corynebacterial species: C. xerosis and C.
minutissimum. The genome sequences of ca. 2.7 Mbp, with a mean number of 2,580 protein en coding genes, were also compared with the publicly available genome sequences of strains of C.
amycolatum and C. striatum. These results will aid the exploration of novel biochemical reactions to
improve existing identification tests as well as the development of more accurate molecular
identification methods through detection of species-specific target genes for isolate’s identification
or drug susceptibility profiling. |