Artigo

Production of L-asparaginase by filamentous fungi

L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% prolin...

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Autor principal: SARQUIS, Maria Inez de Moura
Outros Autores: OLIVEIRA, Edna Maria Morais, SANTOS, Alberdan Silva, COSTA, Gisela Lara da
Grau: Artigo
Idioma: eng
Publicado em: 2013
Assuntos:
Acesso em linha: http://repositorio.ufpa.br/jspui/handle/2011/3310
Resumo:
L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.