Artigo

Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies

The distribution of b-globin gene haplotypes was studied in 209 Amerindians from eight tribes of the Brazilian Amazon: Asurini from Xingú, Awá-Guajá, Parakanã, Urubú-Kaapór, Zoé, Kayapó (Xikrin from the Bacajá village), Katuena, and Tiriyó. Nine different haplotypes were found, two of which (n. 11 a...

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Autor principal: RIBEIRO, Rita de Cassia Mousinho
Outros Autores: SOUSA, Gabriella Pante de, SANTOS, Eduardo José Melo dos, GUERREIRO, João Farias
Grau: Artigo
Idioma: eng
Publicado em: 2013
Assuntos:
Diversidade genética
Polimorfismo genético
Índio
Amazônia brasileira
Acesso em linha: http://repositorio.ufpa.br/jspui/handle/2011/3324
id ir-2011-3324
recordtype dspace
spelling ir-2011-33242019-05-23T11:11:45Z Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies RIBEIRO, Rita de Cassia Mousinho SOUSA, Gabriella Pante de SANTOS, Eduardo José Melo dos GUERREIRO, João Farias Diversidade genética Polimorfismo genético Índio Amazônia brasileira The distribution of b-globin gene haplotypes was studied in 209 Amerindians from eight tribes of the Brazilian Amazon: Asurini from Xingú, Awá-Guajá, Parakanã, Urubú-Kaapór, Zoé, Kayapó (Xikrin from the Bacajá village), Katuena, and Tiriyó. Nine different haplotypes were found, two of which (n. 11 and 13) had not been previously identified in Brazilian indigenous populations. Haplotype 2 (+ - - - -) was the most common in all groups studied, with frequencies varying from 70% to 100%, followed by haplotype 6 (- + + - +), with frequencies between 7% and 18%. The frequency distribution of the b-globin gene haplotypes in the eighteen Brazilian Amerindian populations studied to date is characterized by a reduced number of haplotypes (average of 3.5) and low levels of heterozygosity and intrapopulational differentiation, with a single clearly predominant haplotype in most tribes (haplotype 2). The Parakanã, Urubú-Kaapór, Tiriyó and Xavante tribes constitute exceptions, presenting at least four haplotypes with relatively high frequencies. The closest genetic relationships were observed between the Brazilian and the Colombian Amerindians (Wayuu, Kamsa and Inga), and, to a lesser extent, with the Huichol of Mexico. North-American Amerindians are more differentiated and clearly separated from all other tribes, except the Xavante, from Brazil, and the Mapuche, from Argentina. A restricted pool of ancestral haplotypes may explain the low diversity observed among most present-day Brazilian and Colombian Amerindian groups, while interethnic admixture could be the most important factor to explain the high number of haplotypes and high levels of diversity observed in some South-American and most North-American tribes. 2013-01-15T17:18:16Z 2013-01-15T17:18:16Z 2003 Artigo de Periódico MOUSINHO-RIBEIRO, Rita de Cassia, et al. Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies. Genetics and Molecular Biology, São Paulo, v. 26, n. 3, p. 229-234, 2003. Disponível em: <http://www.scielo.br/pdf/gmb/v26n3/a02v26n3.pdf>. Acesso em: 28 dez. 2012. <http://dx.doi.org/10.1590/S1415-47572003000300002>. 1415-4757 http://repositorio.ufpa.br/jspui/handle/2011/3324 eng Acesso Aberto application/pdf
institution Repositório Institucional - Universidade Federal do Pará
collection RI-UFPA
language eng
topic Diversidade genética
Polimorfismo genético
Índio
Amazônia brasileira
spellingShingle Diversidade genética
Polimorfismo genético
Índio
Amazônia brasileira
RIBEIRO, Rita de Cassia Mousinho
Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
topic_facet Diversidade genética
Polimorfismo genético
Índio
Amazônia brasileira
description The distribution of b-globin gene haplotypes was studied in 209 Amerindians from eight tribes of the Brazilian Amazon: Asurini from Xingú, Awá-Guajá, Parakanã, Urubú-Kaapór, Zoé, Kayapó (Xikrin from the Bacajá village), Katuena, and Tiriyó. Nine different haplotypes were found, two of which (n. 11 and 13) had not been previously identified in Brazilian indigenous populations. Haplotype 2 (+ - - - -) was the most common in all groups studied, with frequencies varying from 70% to 100%, followed by haplotype 6 (- + + - +), with frequencies between 7% and 18%. The frequency distribution of the b-globin gene haplotypes in the eighteen Brazilian Amerindian populations studied to date is characterized by a reduced number of haplotypes (average of 3.5) and low levels of heterozygosity and intrapopulational differentiation, with a single clearly predominant haplotype in most tribes (haplotype 2). The Parakanã, Urubú-Kaapór, Tiriyó and Xavante tribes constitute exceptions, presenting at least four haplotypes with relatively high frequencies. The closest genetic relationships were observed between the Brazilian and the Colombian Amerindians (Wayuu, Kamsa and Inga), and, to a lesser extent, with the Huichol of Mexico. North-American Amerindians are more differentiated and clearly separated from all other tribes, except the Xavante, from Brazil, and the Mapuche, from Argentina. A restricted pool of ancestral haplotypes may explain the low diversity observed among most present-day Brazilian and Colombian Amerindian groups, while interethnic admixture could be the most important factor to explain the high number of haplotypes and high levels of diversity observed in some South-American and most North-American tribes.
format Artigo
author RIBEIRO, Rita de Cassia Mousinho
author2 SOUSA, Gabriella Pante de
SANTOS, Eduardo José Melo dos
GUERREIRO, João Farias
author2Str SOUSA, Gabriella Pante de
SANTOS, Eduardo José Melo dos
GUERREIRO, João Farias
title Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
title_short Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
title_full Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
title_fullStr Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
title_full_unstemmed Genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
title_sort genetic relationships among native americans based on beta-globin gene cluster haplotype frequencies
publishDate 2013
url http://repositorio.ufpa.br/jspui/handle/2011/3324
_version_ 1787149254602522624
score 11.677431

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