Nowadays malaria is considered one of the most iInportant problem of
public health the World Health Organization. Recent studies showed changes in
clinical and laboratory pattern. The aim of this work was to study the clinical
manifestations and laboratory pattern of malaria infection due to Plasmodium
vivax. This longitudinal and prospective study was carried out in Evandro Chagas
Institute, in Belem City, from November 2001 to June 2002. The methodology
was: diagnosis, treatment and follow-up of P. vivax parasites carries diagnosed by
thick smear during all period of the treatment. Were evaluated the
epidemiologycal, clinical and laboratory aspects including sex, skin color,
profession, origin of infection, period of incubation and persistence of headache,
chills and fever, and another symptoms during the treatment. Laboratory
investigation included the parasite count and data related to blood exmnination
(coagulation tests, hemoglobin rates, erythrocytes, leukocytes), aminotransferases,
bilirrubin, alcaline phosphatase, urea and creatinine. Preliminary data of the
present study showed changes in epidemiologycal aspects related to the kind of
occupation of malaria-infected patients living in urban area. The incidence of
malaria cases was higher aIllong students and housewives. This study corroborates
the fonner studies related to chloroquine schizonticide action in an average time of
48/72 hours and also it showed significant thrombocytopenia that still now is not very well studied in malaria due to P. vivax. Plateletes fall do not change the blood
coagulation tests. On day seven, 124 patients among 127, showed paleness, but as
wek now, it has not a good correlation with anelnia occurrence.
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