Na epidemiologic study of Candida sp infection prevalence in non-pregnant women was performed in a population of the north of Brazil (Belem-Pa, 2002). This paper aims to contribute to clear up the infection mechanisms of Candida sp and its possible association to ABO and Lewis group blood antigens and ABH substances secretory status. Such paper comprehended a total of 165 women admitted at the out-patient clinic of "Hospital da Policia Militar" and "Laboratorio de Analises Clinicas do Centro de Ciencias Biologicas da Universidade Federal do Para", who came to those units to undergo gynaecologic examinations, where blood, salive and vaginal mucus samples were taken. Candida sp infection presence was determined through the examination of fresh vaginal secretion and bacterioscopy of vaginal secretion. The identification of ABH and Lewis phenotipes in the blood was determined through direct hemaglutination tests and, in the salive, by Elisa Dot-blot. It was performed a standard form for the obtaining of epidemiologic information. Candida sp prevalation was 47.9%. Among the most commom signals and symptoms associed to Candida sp infections are pruritus and gleet. Women under 40 who did not use condoms and who have already had previous infections presented a higher risk of vulvo-vaginal infection caused by Candida sp. Infected and non-infected women with Candida sp had similar distribuition to the phenotypes of ABO, Lewis blood groups and ABH substances secretory status. And, comparing the expressions of Lewis antigens in the blood, save and vaginal mucus, it was verified that both secretions expressed Lewis antigens without any close relationship to erithrocitic Lewis phenotypes. In such context, it is considered that the nature of genetics diversity in the interaction between Candida sp and host requires more studies involving the identification of different types to determine their probable associations among ABH and Lewis blood groups phenotypes with cadidiasis.
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