Artigo

Papilomavírus humano associado a lesões de cérvice uterina

It was studied the prevalence of human papillomavirus (HPV) among 228 women with lesions of uterine cervix attending the Ofir Loiola Institute, in Belem, Para, from March 1992 to May 1996. Histopathological examination was performed with all cervical biopsy samples obtained from these patients. In a...

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Autor principal: CAVALCANTE, Vânia Lúcia Noronha
Outros Autores: MELLO, Wyller Alencar de, VILLA, Luísa Lina, BRITO, Arival Cardoso de, MACEDO, Roberto Cavalleiro de, BISI, Fátima, SASSAMOTO, Kyio, MONTEIRO, Talita Antonia Furtado, LINHARES, Alexandre da Costa
Grau: Artigo
Idioma: por
Publicado em: 2013
Assuntos:
Acesso em linha: http://repositorio.ufpa.br/jspui/handle/2011/3702
id ir-2011-3702
recordtype dspace
spelling ir-2011-37022019-05-23T13:25:42Z Papilomavírus humano associado a lesões de cérvice uterina Human papillomavirus associated to uterine cervix lesions CAVALCANTE, Vânia Lúcia Noronha MELLO, Wyller Alencar de VILLA, Luísa Lina BRITO, Arival Cardoso de MACEDO, Roberto Cavalleiro de BISI, Fátima SASSAMOTO, Kyio MONTEIRO, Talita Antonia Furtado LINHARES, Alexandre da Costa Papillomavírus humano 16 Papillomavírus humano 18 Colo do útero Neoplasia intra-epitelial cervical Belém - PA Pará - Estado Amazônia brasileira It was studied the prevalence of human papillomavirus (HPV) among 228 women with lesions of uterine cervix attending the Ofir Loiola Institute, in Belem, Para, from March 1992 to May 1996. Histopathological examination was performed with all cervical biopsy samples obtained from these patients. In addition, specimens were analysed by both polimerase chain reaction and dot-blot hybridization to detect HPV DNA. The patients were assigned to three groups, according to the diagnosis made by histopathology, as follows: A, including 155 women suffering from invasive epidermoid carcinoma or adenocarcinoma; B, 54 patients having either cervical intraepithelial neoplasia grade II or III; and C, involving 19 women with chronic cervicitis. The prevalence rates of HPV in groups A, B and C were 70.3%, 63% and 36.8% respectively. HPV 16 accounted for 60.4% and 54.5% of types identified in groups A and B, respectively. Altogether HPV types 16, 18 and 33 were detected in 71.4% of positive patients belonging to group C. Estudou-se a prevalência do papilomavírus humano (HPV) em 228 mulheres portadoras de lesões em cérvice uterina, atendidas no Instituto Ofir Loiola, em Belém, Pará, no período de março de 1992 a maio de 1996. As pacientes foram submetidas à biópsia de colo uterino, sendo o material encaminhado para histopatologia e pesquisa de HPV por PCR e hibridização por dot-blot. Distribuíram-se as participantes em três grupos, conforme diagnóstico histopatológico. O grupo A constituiu-se de 155 mulheres com carcinoma epidermóide invasor ou com adenocarcinoma, o grupo B de 54 portadoras de neoplasia intra-epitelial cervical grau II ou III, e o grupo C de 19 pacientes com cervicite crônica. Observaram-se prevalências de HPV em 70,3%, 63,0% e 36,8% das mulheres dos grupamentos A, B e C, respectivamente, sendo o HPV 16 registrado em 60,4% das amostras positivas do grupo A e 54,5% daquelas do grupo B. Os tipos 16, 18 e 33 representaram 71,4% dos detectados no grupo C. 2013-04-18T13:53:51Z 2013-04-18T13:53:51Z 1999-06 Artigo de Periódico NORONHA, Vânia, et al. Papilomavírus humano associado a lesões de cérvice uterina. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 32, n. 3, p. 235-240, maio/jun. 1999. Disponível em: <http://www.scielo.br/pdf/rsbmt/v32n3/0356.pdf>. Acesso em: 17 abr. 2013. <http://dx.doi.org/10.1590/S0037-86821999000300003>. 0037-8682 http://repositorio.ufpa.br/jspui/handle/2011/3702 por Acesso Aberto application/pdf
institution Repositório Institucional - Universidade Federal do Pará
collection RI-UFPA
language por
topic Papillomavírus humano 16
Papillomavírus humano 18
Colo do útero
Neoplasia intra-epitelial cervical
Belém - PA
Pará - Estado
Amazônia brasileira
spellingShingle Papillomavírus humano 16
Papillomavírus humano 18
Colo do útero
Neoplasia intra-epitelial cervical
Belém - PA
Pará - Estado
Amazônia brasileira
CAVALCANTE, Vânia Lúcia Noronha
Papilomavírus humano associado a lesões de cérvice uterina
topic_facet Papillomavírus humano 16
Papillomavírus humano 18
Colo do útero
Neoplasia intra-epitelial cervical
Belém - PA
Pará - Estado
Amazônia brasileira
description It was studied the prevalence of human papillomavirus (HPV) among 228 women with lesions of uterine cervix attending the Ofir Loiola Institute, in Belem, Para, from March 1992 to May 1996. Histopathological examination was performed with all cervical biopsy samples obtained from these patients. In addition, specimens were analysed by both polimerase chain reaction and dot-blot hybridization to detect HPV DNA. The patients were assigned to three groups, according to the diagnosis made by histopathology, as follows: A, including 155 women suffering from invasive epidermoid carcinoma or adenocarcinoma; B, 54 patients having either cervical intraepithelial neoplasia grade II or III; and C, involving 19 women with chronic cervicitis. The prevalence rates of HPV in groups A, B and C were 70.3%, 63% and 36.8% respectively. HPV 16 accounted for 60.4% and 54.5% of types identified in groups A and B, respectively. Altogether HPV types 16, 18 and 33 were detected in 71.4% of positive patients belonging to group C.
format Artigo
author CAVALCANTE, Vânia Lúcia Noronha
author2 MELLO, Wyller Alencar de
VILLA, Luísa Lina
BRITO, Arival Cardoso de
MACEDO, Roberto Cavalleiro de
BISI, Fátima
SASSAMOTO, Kyio
MONTEIRO, Talita Antonia Furtado
LINHARES, Alexandre da Costa
author2Str MELLO, Wyller Alencar de
VILLA, Luísa Lina
BRITO, Arival Cardoso de
MACEDO, Roberto Cavalleiro de
BISI, Fátima
SASSAMOTO, Kyio
MONTEIRO, Talita Antonia Furtado
LINHARES, Alexandre da Costa
title Papilomavírus humano associado a lesões de cérvice uterina
title_short Papilomavírus humano associado a lesões de cérvice uterina
title_full Papilomavírus humano associado a lesões de cérvice uterina
title_fullStr Papilomavírus humano associado a lesões de cérvice uterina
title_full_unstemmed Papilomavírus humano associado a lesões de cérvice uterina
title_sort papilomavírus humano associado a lesões de cérvice uterina
publishDate 2013
url http://repositorio.ufpa.br/jspui/handle/2011/3702
_version_ 1832605187802398720
score 11.755432