Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea
The hexane extract from the aerial parts of Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) afforded two new epimeric lignans of the type dibenzylbutyrolactol, rel-(8R, 8 S, 9S)-3,4-dimethoxy-3 ,4 -methylenedioxy-9b-ethoxy- and rel-(8R, 8 S, 9R)-3,4-dimethoxy-3 ,4 -methylenedioxy-9a-ethoxy-...
| Autor principal: | SILVA, Ana Paula Freitas da |
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| Outros Autores: | PALMEIRA JUNIOR, Sebastião Ferreira, CONSERVA, Lucia Maria, GUILHON, Giselle Maria Skelding Pinheiro |
| Grau: | Artigo |
| Idioma: | eng |
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2013
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| Acesso em linha: |
http://repositorio.ufpa.br/jspui/handle/2011/3913 |
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ir-2011-3913 |
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ir-2011-39132019-05-23T13:25:54Z Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea SILVA, Ana Paula Freitas da PALMEIRA JUNIOR, Sebastião Ferreira CONSERVA, Lucia Maria GUILHON, Giselle Maria Skelding Pinheiro Análise química Aristolochia peltato-deltoidea Aristolochiaceae Benzofuran neolignan Dibenzylbutyrolactol lignans A-tocopherylquinone Ilha de Maçaranduba - PA Pará - Estado Amazônia brasileira The hexane extract from the aerial parts of Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) afforded two new epimeric lignans of the type dibenzylbutyrolactol, rel-(8R, 8 S, 9S)-3,4-dimethoxy-3 ,4 -methylenedioxy-9b-ethoxy- and rel-(8R, 8 S, 9R)-3,4-dimethoxy-3 ,4 -methylenedioxy-9a-ethoxy-lignans-8.8 ,9.O.9 , besides a benzofuran neolignan, known as eupomatenoid-7, a-tocopherylquinone, b-sitosterol and stigmasterol. From the chloroform extract were isolated two diastereomeric dibenzylbutyrolactone lignans: rel-(8R, 8 R)- and rel-(8R, 8 S)-3,4-dimethoxy-3 ,4 -methylenedioxy-9-oxo-lignans-8.8 ,9.O.9 . Chemical composition analysis by GC/MS of the non polar fractions from the hexane extract was also carried out and ten components were identified. The structures of the isolated compounds were elucidated utilizing spectrometric methods. Do extrato hexânico das partes aéreas de Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) foram isolados duas novas lignanas epiméricas do tipo dibenzilbutirolactol, rel-(8R, 8 S, 9S)-3,4-dimetoxi-3 ,4 -metilenodioxi-9b-etoxi- e rel-(8R, 8 S, 9R)-3,4-dimetoxi-3 ,4 -metilenodioxi-9a-etoxi-lignanas-8.8 ,9.O.9 , além da neolignana benzofurânica eupomatenóide-7, a-tocoferilquinona, b-sitosterol e estigmasterol. Do extrato clorofórmico foram isoladas duas lignanas dibenzilbutirolactonas diasteroisoméricas: rel-(8R, 8 R)- e rel-(8R, 8 S)-3,4-dimetoxi-3 ,4 -metilenodioxi-9-oxo-lignanas-8.8 ,9.O.9 . A composição química das frações apolares do extrato hexânico também foi analisada por CG/EM. Dentre os componentes detectados, dez foram identificados. As estruturas dos compostos isolados foram elucidadas utilizando-se métodos espectrométricos. 2013-05-28T13:00:16Z 2013-05-28T13:00:16Z 1999-04 Artigo de Periódico SILVA, Ana Paula Freitas da, et al. Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea. Journal of the Brazilian Chemical Society, São Paulo, v. 10, n. 2, p. 122-126, mar./abr. 1999. Disponível em: <http://www.scielo.br/pdf/jbchs/v10n2/a09v10n2.pdf>. Acesso em: 27 maio 2013. <http://dx.doi.org/10.1590/S0103-50531999000200009>. 1678-4790 0103-5053 http://repositorio.ufpa.br/jspui/handle/2011/3913 eng Acesso Aberto application/pdf |
| institution |
Repositório Institucional - Universidade Federal do Pará |
| collection |
RI-UFPA |
| language |
eng |
| topic |
Análise química Aristolochia peltato-deltoidea Aristolochiaceae Benzofuran neolignan Dibenzylbutyrolactol lignans A-tocopherylquinone Ilha de Maçaranduba - PA Pará - Estado Amazônia brasileira |
| spellingShingle |
Análise química Aristolochia peltato-deltoidea Aristolochiaceae Benzofuran neolignan Dibenzylbutyrolactol lignans A-tocopherylquinone Ilha de Maçaranduba - PA Pará - Estado Amazônia brasileira SILVA, Ana Paula Freitas da Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea |
| topic_facet |
Análise química Aristolochia peltato-deltoidea Aristolochiaceae Benzofuran neolignan Dibenzylbutyrolactol lignans A-tocopherylquinone Ilha de Maçaranduba - PA Pará - Estado Amazônia brasileira |
| description |
The hexane extract from the aerial parts of Aristolochia peltato-deltoidea Hoehne (Aristolochiaceae) afforded two new epimeric lignans of the type dibenzylbutyrolactol, rel-(8R, 8 S, 9S)-3,4-dimethoxy-3 ,4 -methylenedioxy-9b-ethoxy- and rel-(8R, 8 S, 9R)-3,4-dimethoxy-3 ,4 -methylenedioxy-9a-ethoxy-lignans-8.8 ,9.O.9 , besides a benzofuran neolignan, known as eupomatenoid-7, a-tocopherylquinone, b-sitosterol and stigmasterol. From the chloroform extract were isolated two diastereomeric dibenzylbutyrolactone lignans: rel-(8R, 8 R)- and rel-(8R, 8 S)-3,4-dimethoxy-3 ,4 -methylenedioxy-9-oxo-lignans-8.8 ,9.O.9 . Chemical composition analysis by GC/MS of the non polar fractions from the hexane extract was also carried out and ten components were identified. The structures of the isolated compounds were elucidated utilizing spectrometric methods. |
| format |
Artigo |
| author |
SILVA, Ana Paula Freitas da |
| author2 |
PALMEIRA JUNIOR, Sebastião Ferreira CONSERVA, Lucia Maria GUILHON, Giselle Maria Skelding Pinheiro |
| author2Str |
PALMEIRA JUNIOR, Sebastião Ferreira CONSERVA, Lucia Maria GUILHON, Giselle Maria Skelding Pinheiro |
| title |
Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea |
| title_short |
Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea |
| title_full |
Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea |
| title_fullStr |
Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea |
| title_full_unstemmed |
Two Dibenzylbutyrolactol derivatives and other chemical constituents from Aristolochia peltato-deltoidea |
| title_sort |
two dibenzylbutyrolactol derivatives and other chemical constituents from aristolochia peltato-deltoidea |
| publishDate |
2013 |
| url |
http://repositorio.ufpa.br/jspui/handle/2011/3913 |
| _version_ |
1787149147716976640 |
| score |
11.674684 |