Artigo

Alterações clínicolaboratoriais em pacientes com malária por Plasmodium vivax e deficiência de glicose-6-fosfato desidrogenase tratados com 0,50mg/kg/dia de primaquina

The adverse effects of primaquine (0.50mg/kg/day) were investigated in eleven patients with vivax malaria (three patients with glucose-6-phosphate dehydrogenase deficiency). Clinical and laboratorial alterations indicated acute hemolysis in only the enzymopenic patients and treatment was interrupted...

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Autor principal: SILVA, Mônica Cristina de Moraes
Outros Autores: SANTOS, Eliane Barbosa, COSTA, Elenild de Góes, SILVA FILHO, Manoel Gomes da, GUERREIRO, João Farias, PÓVOA, Marinete Marins
Grau: Artigo
Idioma: por
Publicado em: 2013
Assuntos:
Acesso em linha: http://repositorio.ufpa.br/jspui/handle/2011/4277
Resumo:
The adverse effects of primaquine (0.50mg/kg/day) were investigated in eleven patients with vivax malaria (three patients with glucose-6-phosphate dehydrogenase deficiency). Clinical and laboratorial alterations indicated acute hemolysis in only the enzymopenic patients and treatment was interrupted. Our results suggest that screening for G6PD deficiency should be carried out in patients with vivax malaria infection in order to avoid complications due to primaquine.