Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by c...
| Autor principal: | PINHEIRO, Eduardo Antonio Abreu |
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| Outros Autores: | CARVALHO, Josiwander Miranda, SANTOS, Diellem Cristina Paiva dos, FEITOSA, André de Oliveira, MARINHO, Patrícia Santana Barbosa, GUILHON, Giselle Maria Skelding Pinheiro, SANTOS, Lourivaldo da Silva, SOUZA, Afonso Duarte Leão de, MARINHO, Andrey Moacir do Rosário |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
2014
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| Acesso em linha: |
http://repositorio.ufpa.br/jspui/handle/2011/4553 |
| Resumo: |
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The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity. |