Active polyketides isolated from Penicillium herquei
In this work we are reporting the isolation by classical methods of chromatography of six polyketides from Penicillium herquei. The compounds citreorosein ( 1) , emodin ( 2) , janthinone ( 3) , citrinin ( 4) , citrinin H1 ( 5) and dicitrinol ( 6) were identified by spectral methods of 1D and 2D NMR...
| Autor principal: | MARINHO, Andrey Moacir do Rosário |
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| Outros Autores: | MARINHO, Patrícia Santana Barbosa, SANTOS, Lourivaldo da Silva, RODRIGUES FILHO, Edson, FERREIRA, Izabel Cristina Piloto |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: |
http://repositorio.ufpa.br/jspui/handle/2011/4554 |
| Resumo: |
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In this work we are reporting the isolation by classical methods of chromatography of six polyketides from Penicillium herquei. The compounds citreorosein ( 1) , emodin ( 2) , janthinone ( 3) , citrinin ( 4) , citrinin H1 ( 5) and dicitrinol ( 6) were identified by spectral methods of 1D and 2D NMR and MS. Compounds 1, 2 and 3 were tested against promastigotes forms of Leishmania brasiliensis and 1 and 2 were also assayed against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis and showed good activity. |