/img alt="Imagem da capa" class="recordcover" src="""/>
Dissertação
Avaliação do nível de concordância do teste imunocromatográfico OptiMAL-IT® e a gota espessa no diagnóstico da malária, no município de Mazagão-AP, Brasil
The precocious diagnosis and the opportune treatment of the cases of malaria is one of the main strategies for the control of the disease. Several alternatives for the traditional microscopic diagnosis were proposed in the last years, the Immunochromatographic tests that capture white antigens of...
Autor principal: | FADUL, Danielle Scerne |
---|---|
Grau: | Dissertação |
Idioma: | por |
Publicado em: |
Universidade Federal do Pará
2014
|
Assuntos: | |
Acesso em linha: |
http://repositorio.ufpa.br/jspui/handle/2011/4773 |
Resumo: |
---|
The precocious diagnosis and the opportune treatment of the cases of malaria
is one of the main strategies for the control of the disease. Several alternatives
for the traditional microscopic diagnosis were proposed in the last years, the
Immunochromatographic tests that capture white antigens of the parasites of
the malaria they are being proposed, as the test OptiMAL-IT® that captures the
lactic desidrogenase of the Plasmodium sp.. The study had as objective the
evaluation of the level of agreement between the Immunochromatographic test
(OptiMAL-IT®) and the thick drop for the diagnosis of the malaria in the City of
Mazagão – Amapá, Brazil. 413 individuals were analyzed with malaria
sintomatology that had looked for the service of the unit of health service of the
city, with age among 01-68 years. The results of the OptiMAL-IT® test were
compared with the obtained results, of the same samples, through the thick
drop red-faced by the Giemsa. Of the 413 patients suspicious to present
malaria, 317(76.8%) were positive through GE and 311 (75.3%) were positive
for TDR OptiMAL-IT®. Of the positive blades of GE, had been found 27.4% of
P. falciparum and 72.6% of P. vivax . The OptiMAL-IT® test detected 27.7% of
P. falciparum and 72.3% of P. vivax. The sensibility obtained with TDR for P.
falciparum was of 97.7% and for P. vivax was of 98.2%, the global sensibility of
TDR was of 98.1% and the global specificity for both the species was of 100%.
They were found preditivos values positive and negative of 100% and 94.1%,
respectively. The OptiMAL-IT® test had a high agreement with thick drop, it is
specific and efficient. It can be used in the diagnosis of malaria in the situations
where microscopy is not available. |