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Dissertação
Investigação fitoquímica biomonitorada da tintura 70% de Arrabidaea chica (Humb. & Bompl.) Verlot
The Arrabidaea chica (H & B) Verlot, popularly known as Pariri or crajirú. Scandentia is a small shrub about 2.5 m high, occurring from southern Mexico to central Brazil, is common in the Amazon, where it is used by Indians for body painting.Popularly tea leaves is indicated for inflammation, ane...
Autor principal: | RIBEIRO, Jeane Francisca Alves |
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Grau: | Dissertação |
Idioma: | por |
Publicado em: |
Universidade Federal do Pará
2014
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Assuntos: | |
Acesso em linha: |
http://repositorio.ufpa.br/jspui/handle/2011/5638 |
Resumo: |
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The Arrabidaea chica (H & B) Verlot, popularly known as Pariri or crajirú. Scandentia
is a small shrub about 2.5 m high, occurring from southern Mexico to central Brazil, is
common in the Amazon, where it is used by Indians for body painting.Popularly tea
leaves is indicated for inflammation, anemia, intestinal cramps, regulate
menstruation, diarrhea, among others. Recent studies have shown its antioxidant
activity and wound healing in vivo and in vitro, and antifungal activity against
Trichophyton mentagrophytes and trypanocidal effect. This paper aims to contribute
to the validation of the claim of use and to standardize the form of employment A.
chica herbal medicine as a resource, since it is in RENISUS. The ethanolic and
aqueous extracts of the plant were investigated for their secondary metabolites.
Parameters were determined for quality control of the plant drug, through grading,
drying powder loss and total ash.Besides the chromatographic profiles obtained by
TLC, CLV, LC-MS and LC - DAD. The plant meets the parameters of quality control
in accordance with the literature. A CCD profile obtained with the eluent Hexane /
Acetone / MeOH (67,5:27,5:5) and revealed with NP / PEG revealed a band with Rf =
0.17 with yellow fluorescence characteristic of flavonoids. In the profile of HPLC -
DAD chromatograms were obtained with characteristics of quinones and flavonoids
as well. From these results, the work was directed to the isolation, initially with the
FAE by fractionation of CLV and analysis of resulting fractions by HPLC-DAD, and as
a result suggested the presence of a flavonoid apigenin derivative of the flavonol.
The microbiological results corroborate some of its popular uses thus contributing to
validate the form of alleged use of the plant. |