Artigo

Artrite enteropática no Brasil: dados do registro brasileiro de espondiloartrites

Inflammatory bowel diseases (Crohn’s disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. Methods: Prospective, observational, multicenter study with patients from 29 reference centers participati...

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Autor principal: RESENDE, Gustavo Gomes
Outros Autores: LANNA, Cristina Costa Duarte, BERTOLUZZO, Adriana Bruscato, GONÇALVES, Celio Roberto, XIMENES, Antonio Carlos, BERTOLO, Manoel Barros, KEISERMAN, Mauro Waldemar, MENIN, Rita de Cássia, SKARE, Thelma Larocca, CARNEIRO, Sueli Coelho da Silva, AZEVEDO, Valderílio Feijó, VIEIRA, Walber Pinto, BIANCHI, Washington Alves, BONFIGLIOLI, Rubens, CAMPANHOLO, Cristiano Barbosa, CARVALHO, Hellen Mary da Silveira de, COSTA, Izaias Pereira da, DUARTE, Angela Luzia Branco Pinto, KOHEM, Charles Lubianca, MEIRELLES, Eduardo de Souza, PEREIRA, Ivânio Alves, PINHEIRO, Marcelo de Medeiros, POLITO, Elizandra Tomazela Laurenti, ROCHA, Francisco Airton Castro da, SANTIAGO, Mittermayer Barreto, CUNHA, Maria de Fátima Lobato da, VALIM, Valéria, BARROS, Percival Degrava Sampaio, RIBEIRO, Sandra Lúcia Euzébio, SILVA, José Antonio Braga da, ALBUQUERQUE, Elisa N., LEITE, Nocy, LIMA, Sonia A. L.
Grau: Artigo
Idioma: por
Publicado em: Universidade Federal do Pará 2018
Assuntos:
Artrite enteropática
Doença de Crohn
Retocolite ulcerativa
Estudos de registro
CNPQ::CIENCIAS DA SAUDE
Acesso em linha: http://repositorio.ufpa.br/jspui/handle/2011/9632
http://dx.doi.org/10.1016/j.rbr.2013.04.001
Resumo:
Inflammatory bowel diseases (Crohn’s disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. Methods: Prospective, observational, multicenter study with patients from 29 reference centers participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the assessment of axial mobility, quality of life, enthesitic involvement, disease activity and functional capacity were applied. Laboratory and radiographic examinations were performed. The aim of this study is to compare the clinical, epidemiological, genetic, imaging, treatment and prognosis characteristics of patients with enteropathic arthritis with other types of spondyloarthritis in a large Brazilian cohort. Results: A total of 3.2% of patients were classified as having enteroarthritis, 2.5% had spondylitis and 0.7%, arthritis (peripheral predominance). The subgroup of individuals with enteroarthritis had a higher prevalence in women (P < 0.001), lower incidence of inflammatory axial pain (P < 0.001) and enthesitis (P = 0.004). HLA-B27 was less frequent in the group with enteroarthritis (P = 0.001), even when considering only those with the pure axial form. There was a lower prevalence of radiographic sacroiliitis (P = 0.009) and lower radiographic score (BASRI) (P = 0.006) when compared to patients with other types of spondyloarthritis. They also used more corticosteroids (P < 0.001) and sulfasalazine (P < 0.001) and less nonsteroidal anti-inflammatory drugs (P < 0.001) and methotrexate (P = 0.001). Conclusion: There were differences between patients with enteroarthritis and other types of spondyloarthritis, especially higher prevalence of females, lower frequency of HLA-B27, associated with less severe axial involvement.

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