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Resumo Apresentado em Evento
The Leishmania-sandfhy interface
The factors affecting the behaviour of Leishmania in sandflies are described against the background of our knowledge of the basic hfe cycles o f suprapylarian and p e r i p y l a r i a n species. A diagrammatic representation is used to tabulate a variety of known and possible interactions between...
Autor principal: | Molyneux, D.H |
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Outros Autores: | Ryan. L, Lainson, Ralph, Shaw, Jeffrey Jon |
Grau: | Resumo Apresentado em Evento |
Idioma: | eng |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: |
http://patua.iec.gov.br/handle/iec/2566 |
Resumo: |
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The factors affecting the behaviour of Leishmania in sandflies are described against the
background of our knowledge of the basic hfe cycles o f suprapylarian and p e r i p y l a r i a n species. A diagrammatic
representation is used to tabulate a variety of known and possible interactions between parasite and
sandfly based on our knowledge of other trypanosomatid-insect associations. The physical interactions
between Leishmania and sandfly are described and the ?reas of productive f u r t h e r study highlighted.
The n a t u r a l Leishmania-ssLn?r?y combination, L . amazonensis in Lutzomyia flaviscutellata, is discussed
i n the l i g h t of recent results and compared w i t h earlier findings on host parasite associations. The f i n d i ng
of promastigote infections i n the oesophageal d i v e r t i c u l um is described in t h i s system; the significance of
such a f i n d i n g is unknown. This observation is discussed i n the l i g h t of present ideas on the relationships
between Leishmania promastigotes and carbohydrates, carbohydrates on i n h i b i t i o n of agglutination, insect
lectins and Leishmania transmission. I t is emphasised t h a t the interactions w i l l be complex and species
specific, w h i l s t modulated by carbohydrates derived f r om a variety of plant sources. Generalisations about
such interactions i n the field may be d i f f i c u l t to predict. |