An outbreak of rotavirus diarrhea among a nonimmune, isolated South American Indian Community
During July-August 1977, an outbreak of acute diarrhea occurred in an unusually isolated population, lhe Tiriy? Indians, who live in lhe north of Par?, Brazil, near lhe border with Surinam. Diarrhea was reported by 157 (70%) of lhe 224 Indians living in lhe village during lhe epidemic. There was...
| Autor principal: | Linhares, Alexandre da Costa |
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| Outros Autores: | Pinheiro, Francisco de Paula, Freitas, Ronaldo Barros de, Gabbay, Yvone Benchimol, Shirley, Jane A, Beards, Graham M |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: |
http://patua.iec.gov.br//handle/iec/2707 |
| Resumo: |
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During July-August 1977, an outbreak of acute diarrhea occurred in an
unusually isolated population, lhe Tiriy? Indians, who live in lhe north of Par?,
Brazil, near lhe border with Surinam. Diarrhea was reported by 157 (70%) of
lhe 224 Indians living in lhe village during lhe epidemic. There was one fatal
case in a one year old child. Rotavirus was detected by electron microscopy
in one fecal specimen collected from an acute case of diarrhea. Seroconversions
were noted in 127 out of 168 (75.6%) paired serum samples tested for
rotavirus antibody by counter-immunoelectrophoresis. With immunofluorescence
based neutralization tests, rotavirus serotype 1 (Birmingham) was
shown to be associated with lhe outbreak. The infection also boosted type
3 antibodies but this was most apparent in persons with pre-existing type 3
titers and lhe boost was not as great as with type 1. Ali age groups were affected.
The proportion symptomatic was greatest in young children. |