Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses

Bezerra, Delana A. M.; Guerra, Sylvia de F?tima dos Santos; Serra, Ana C. S.; Fecury, Priscylla C. M. S.; Bandeira, Renato S.; Penha J?nior, Edvaldo T.; Lobo, Patr?cia S.; Sousa Junior, Edivaldo Costa; Linhares, Alexandre da Costa; Soares, Luana Souza; Mascarenhas, Joana D'Arc Pereira

Artigo

Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses

The species A rotaviruses (RVA) are important gastroenteric pathogens that infect humans and animals. RVA genotype G3P[9] has been described in human-animal reassortment events, and the complexity of its hosts motivates the genetic investigation of this strain. Therefore, the aim of this study is to...

ver descrição completa

Autor principal:	Bezerra, Delana A. M.
Outros Autores:	Guerra, Sylvia de F?tima dos Santos, Serra, Ana C. S., Fecury, Priscylla C. M. S., Bandeira, Renato S., Penha J?nior, Edvaldo T., Lobo, Patr?cia S., Sousa Junior, Edivaldo Costa, Linhares, Alexandre da Costa, Soares, Luana Souza, Mascarenhas, Joana D'Arc Pereira
Grau:	Artigo
Idioma:	eng
Publicado em:	Wiley 2017
Assuntos:	Rotavirus / isolamento & purifica??o Rotavirus / gen?tica Gastroenterite / virologia Infec??es por Rotavirus / virologia V?rus Reordenados / gen?tica Recombina??o Gen?tica Filogenia Gen?tipo Evolu??o Molecular An?lise de Sequ?ncia de DNA Rea??o em Cadeia da Polimerase Via Transcriptase Reversa / m?todos
Acesso em linha:	http://patua.iec.gov.br//handle/iec/2848

id	ir-iec-2848
recordtype	dspace
spelling	ir-iec-28482019-04-26T18:38:33Z Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses Bezerra, Delana A. M. Guerra, Sylvia de F?tima dos Santos Serra, Ana C. S. Fecury, Priscylla C. M. S. Bandeira, Renato S. Penha J?nior, Edvaldo T. Lobo, Patr?cia S. Sousa Junior, Edivaldo Costa Linhares, Alexandre da Costa Soares, Luana Souza Mascarenhas, Joana D'Arc Pereira Rotavirus / isolamento & purifica??o Rotavirus / gen?tica Gastroenterite / virologia Infec??es por Rotavirus / virologia V?rus Reordenados / gen?tica Recombina??o Gen?tica Filogenia Gen?tipo Evolu??o Molecular An?lise de Sequ?ncia de DNA Rea??o em Cadeia da Polimerase Via Transcriptase Reversa / m?todos The species A rotaviruses (RVA) are important gastroenteric pathogens that infect humans and animals. RVA genotype G3P[9] has been described in human-animal reassortment events, and the complexity of its hosts motivates the genetic investigation of this strain. Therefore, the aim of this study is to analyse a G3P[9] sample that was detected in a child with acute gastroenteritis. The 1A3739 sample featured the constellation G3P[9]-I18-R3-C3-Mx-A19-N3-T3-E3-H6. The sequence for VP3 gene was not obtained. The phylogeny showed a closer relationship among genes VP7, VP1, NSP3, NSP4, and NSP5 with genes of animal origin, such as chiropter, alpaca, equine, and simian. In addition, the genes VP6 and NSP1 belong to the new genotypes I18 and A19, respectively. The emergence of strains such as these can interfere with the effectiveness of the RVA vaccine, and continuous monitoring is therefore important. Additional studies are needed to determine the evolutionary source and to identify a possible reservoir of RVA in nature. 2017-11-14T17:00:52Z 2017-11-14T17:00:52Z 2017 Artigo BEZERRA, Delana A. M. et al. Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses. Journal of Medical Virology, v. 89, n. 6, p. 974-981, June 2017. 0146-6615 http://patua.iec.gov.br//handle/iec/2848 10.1002/jmv.24733 eng Acesso Embargado application/pdf Wiley
institution	Instituto Evandro Chagas (IEC)
collection	PATUA
language	eng
topic	Rotavirus / isolamento & purifica??o Rotavirus / gen?tica Gastroenterite / virologia Infec??es por Rotavirus / virologia V?rus Reordenados / gen?tica Recombina??o Gen?tica Filogenia Gen?tipo Evolu??o Molecular An?lise de Sequ?ncia de DNA Rea??o em Cadeia da Polimerase Via Transcriptase Reversa / m?todos
spellingShingle	Rotavirus / isolamento & purifica??o Rotavirus / gen?tica Gastroenterite / virologia Infec??es por Rotavirus / virologia V?rus Reordenados / gen?tica Recombina??o Gen?tica Filogenia Gen?tipo Evolu??o Molecular An?lise de Sequ?ncia de DNA Rea??o em Cadeia da Polimerase Via Transcriptase Reversa / m?todos Bezerra, Delana A. M. Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
topic_facet	Rotavirus / isolamento & purifica??o Rotavirus / gen?tica Gastroenterite / virologia Infec??es por Rotavirus / virologia V?rus Reordenados / gen?tica Recombina??o Gen?tica Filogenia Gen?tipo Evolu??o Molecular An?lise de Sequ?ncia de DNA Rea??o em Cadeia da Polimerase Via Transcriptase Reversa / m?todos
description	The species A rotaviruses (RVA) are important gastroenteric pathogens that infect humans and animals. RVA genotype G3P[9] has been described in human-animal reassortment events, and the complexity of its hosts motivates the genetic investigation of this strain. Therefore, the aim of this study is to analyse a G3P[9] sample that was detected in a child with acute gastroenteritis. The 1A3739 sample featured the constellation G3P[9]-I18-R3-C3-Mx-A19-N3-T3-E3-H6. The sequence for VP3 gene was not obtained. The phylogeny showed a closer relationship among genes VP7, VP1, NSP3, NSP4, and NSP5 with genes of animal origin, such as chiropter, alpaca, equine, and simian. In addition, the genes VP6 and NSP1 belong to the new genotypes I18 and A19, respectively. The emergence of strains such as these can interfere with the effectiveness of the RVA vaccine, and continuous monitoring is therefore important. Additional studies are needed to determine the evolutionary source and to identify a possible reservoir of RVA in nature.
format	Artigo
author	Bezerra, Delana A. M.
author2	Guerra, Sylvia de F?tima dos Santos Serra, Ana C. S. Fecury, Priscylla C. M. S. Bandeira, Renato S. Penha J?nior, Edvaldo T. Lobo, Patr?cia S. Sousa Junior, Edivaldo Costa Linhares, Alexandre da Costa Soares, Luana Souza Mascarenhas, Joana D'Arc Pereira
author2Str	Guerra, Sylvia de F?tima dos Santos Serra, Ana C. S. Fecury, Priscylla C. M. S. Bandeira, Renato S. Penha J?nior, Edvaldo T. Lobo, Patr?cia S. Sousa Junior, Edivaldo Costa Linhares, Alexandre da Costa Soares, Luana Souza Mascarenhas, Joana D'Arc Pereira
title	Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
title_short	Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
title_full	Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
title_fullStr	Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
title_full_unstemmed	Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
title_sort	analysis of a genotype g3p9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses
publisher	Wiley
publishDate	2017
url	http://patua.iec.gov.br//handle/iec/2848
_version_	1717584345457229824
score	11.755432

Analysis of a genotype G3P9 rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses

Registros relacionados