Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae
Triniti virus (TNTV) has been isolated in Trinidad and Tobago and in Brazil. To date little is known about this virus, which is classified as an ungrouped virus within the family Togaviridae. Here, three isolates of TNTV were characterized both genetically and antigenically. The genome was shown t...
| Autor principal: | Lima, Juliana Abreu |
|---|---|
| Outros Autores: | Nunes Neto, Joaquim Pinto, Castro, Karoline Silva, Rosa, Am?lia Paes de Andrade Travassos da, Tesh, Robert, Nunes, M?rcio Roberto Teixeira, Popov, Vsevolod Leonidovich, Vasilakis, Nikos, Guzman, Hilda, Widen, Steven, Silva, Sandro Patroca da, Medeiros, Daniele Barbosa de Almeida, Cardoso, Jedson Ferreira, Martins, L?via Caricio, Azevedo, Raimunda do Socorro da Silva, Vasconcelos, Pedro Fernando da Costa, Chiang, Jannifer Oliveira |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
Microbiology Society
2019
|
| Assuntos: | |
| Acesso em linha: |
http://patua.iec.gov.br//handle/iec/3596 |
| Resumo: |
|---|
|
Triniti virus (TNTV) has been isolated in Trinidad and Tobago and in Brazil. To date little is known about this virus, which is
classified as an ungrouped virus within the family Togaviridae. Here, three isolates of TNTV were characterized both
genetically and antigenically. The genome was shown to contain three RNA segments: small (S), medium (M) and large (L).
Genome organization, protein sizes and protein motifs were similar to those of viruses in the genus Orthobunyavirus, family
Peribunyaviridae. Antigenic reactivity revealed the three TNTV isolates to be closely related, but no serologic cross-reaction
with other orthobunyaviruses. Morphological observation by transmission electron microscopy indicated that virus size and
symmetry were compatible with those of viruses in the family Peribunyaviridae. Our serological, morphological and
molecular results support the taxonomic reclassification of TNTV as a member of the genus Orthobunyavirus, family
Peribunyaviridae. |