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Artigo
Whole-genome sequencing of parvoviruses from wild and domestic animals in Brazil provides new insights into parvovirus distribution and diversity
Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many parvoviral pathogens of medical, veterinary and ecological importance have been identified. In this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses infecting wild and do...
Autor principal: | Souza, William Marciel de |
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Outros Autores: | Dennis, Tristan Philip Wesley, Fumagalli, Marc?lio Jorge, Araujo, Jansen de, Santos Jr, Gilberto Sabino, Maia, Felipe Gon?alves Motta, Acrani, Gustavo Olszanski, Carrasco, Adriano de Oliveira Torres, Romeiro, Marilia Farignoli, Modha, Sejal, Vieira, Luiz Carlos, Ometto, Tatiana Lopes, Queiroz, Luzia Helena, Durigon, Edison Luiz, Nunes, Marcio Roberto Teixeira, Figueiredo, Luiz Tadeu Moraes, Gifford, Robert James |
Grau: | Artigo |
Idioma: | eng |
Publicado em: |
Cold Spring Harbor Laboratory
2019
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Assuntos: | |
Acesso em linha: |
http://patua.iec.gov.br//handle/iec/3866 |
Resumo: |
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Parvoviruses (family Parvoviridae) are small, single-stranded DNA viruses. Many
parvoviral pathogens of medical, veterinary and ecological importance have been identified. In
this study, we used high-throughput sequencing (HTS) to investigate the diversity of parvoviruses
infecting wild and domestic animals in Brazil. We identified 21 parvovirus sequences (including
twelve nearly complete genomes and nine partial genomes) in samples derived from rodents, bats,
opossums, birds and cattle in Pernambuco, S?o Paulo, Paran? and Rio Grande do Sul states. These
sequences were investigated using phylogenetic and distance-based approaches, and were thereby
classified into eight parvovirus species (six of which have not been described previously),
representing six distinct genera in the subfamily Parvovirinae. Our findings extend the known
biogeographic range of previously characterized parvovirus species, and the known host range of
three parvovirus genera (Dependovirus, Aveparvovirus, and Tetraparvovirus). Moreover, our
investigation provides a window into the ecological dynamics of parvovirus infections in
vertebrates, revealing that many parvovirus genera contain well-defined sub-lineages that
circulate widely throughout the world within particular taxonomic groups of hosts. |