Genomic profiling reveals the pivotal role of hrHPV driving copy number and gene expression alterations, including mRNA downregulation of TP53 and RB1 in penile cancer
The incidence of penile cancer (PeCa) is increasing worldwide, however, the highest rates are reported in underdeveloped countries. The molecular mechanisms that underly the onset and progression of these tumors are still unclear. Therefore, our goal was to determine the genome?wide copy number alte...
| Autor principal: | Macedo, Juliana |
|---|---|
| Outros Autores: | Silva, Elis, Nogueira, Leudivan, Coelho, Ronald, Silva, Jenilson da, Santos, Alcione dos, Teixeira J?nior, Ant?nio Augusto, Belfort, Marta, Silva, Gyl, Khayat, Andr?, Oliveira, Edivaldo Herculano Corr?a de, Santos, Ana Paula dos, Cavalli, Luciane R, Pereira, Silma Regina |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
Wiley
2020
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| Assuntos: | |
| Acesso em linha: |
http://patua.iec.gov.br//handle/iec/4080 |