Human papillomavirus (HPV) is the most common sexually transmitted infection in the
world. Several studies have shown a higher prevalence of HPV infection in HIV-infected
women. The aim of this study was to determine the prevalence and the genotype diversity
of HPV infection in HIV-infected women. From April 2010 to December 2012 cervical
specimens were collected from 169 HIV-infected women who screening for cervical
cancer at Reference Unit in Bel?m. The detection of HPV infection was performed by
nested PCR and HPV type was performed using a commercial system. The prevalence
of HPV infection was 63.3%. Of the 47 genotyped samples, 40.4% was found positive
for high risk-HPV 16 and 12.8% for high risk-HPV 52. HPV infection was predominant in
the group of women with no incidence of cytological abnormalities and more prevalent
in women of reproductive age, unmarried, low education level, and who reported use
condoms during sexual intercourse. It was observed an association between HPV
infection and independent variables, such as condom use, multiple sexual partners,
and history of sexually transmitted diseases. High-risk types of HPV infection were
prevalent in our study. Infection with multiple high-risk HPV genotypes may potentiate
the development of cervical cancer in HIV-infected women.
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