Jejunal injuries in captive marmosets affected by chronic wasting disease
INTRODUCTION: Wasting marmoset syndrome affects the Callitrichidae family reared in captivity, characterized by progressive muscle-weakening and wasting conditions. It has been one of the main causes of death in primates of this genus. OBJECTIVE: To evaluate the existence of histopathological and...
| Autor principal: | Pereira, Washington Luiz Assun??o |
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| Outros Autores: | Diniz J?nior, Jos? Ant?nio Pican?o, Muniz, Jos? Augusto Pereira Carneiro, Souza, Alex Junior Souza de, Mendes, Fernanda Figueiredo, Cecim, Amanda Desir?e Assun??o, Aguirra, Lucien Roberta Valente Miranda de |
| Grau: | Artigo |
| Idioma: | eng |
| Publicado em: |
MS/SVS/Instituto Evandro Chagas
2021
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| Assuntos: | |
| Acesso em linha: |
http://patua.iec.gov.br//handle/iec/4385 |
| Resumo: |
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INTRODUCTION: Wasting marmoset syndrome affects the Callitrichidae family reared in captivity, characterized by
progressive muscle-weakening and wasting conditions. It has been one of the main causes of death in primates of this
genus. OBJECTIVE: To evaluate the existence of histopathological and ultrastructural alterations in jejunal of marmosets
that presented a clinical history of the progressive wasting disease in relation to healthy animals. MATERIALS AND
METHODS: Jejunal biopsies of seven marmosets were performed: five of them, two specimens of Callithrix jacchus
and three Callithrix penicillata, were affected by clinical signs of progressive weight loss and muscle weakness; and two
healthy animals, one of each cited species, were used as control animals. RESULTS: Marmosets with a clinical history
of progressive weight loss presented jejunal villus atrophy with a flattened surface; also the goblet cells were scarce and
barely functional compared to the control animals. CONCLUSION: These changes can cause malabsorption of nutrients
and promote the progressive weight loss of callitrichids. |