Trabalho de Conclusão de Curso - Graduação

Efeito do exercício físico em parâmetros bioquímicos e histológicos de ratos submetidos a tenotomia do tendão calcâneo

Tendinopathy is an injury that affects the tents and is characterized by chronic pain, the formation from partial or total of the affected tissue. Regular tendons affect the calcaneus tendon. In the process of diagnosis of this tissue there are active substances modulated in the healing process, an...

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Autor principal: LEITE, Ewellin Thamires Alencar
Grau: Trabalho de Conclusão de Curso - Graduação
Publicado em: 2019
Assuntos:
Acesso em linha: http://bdm.ufpa.br/jspui/handle/prefix/2072
Resumo:
Tendinopathy is an injury that affects the tents and is characterized by chronic pain, the formation from partial or total of the affected tissue. Regular tendons affect the calcaneus tendon. In the process of diagnosis of this tissue there are active substances modulated in the healing process, an example of lactate and a glycemia. Regarding the therapeutic techniques, it is necessary to discuss the physical effect on the repair process, and, indeed, the practice of the same implement in the modulation of glucose and lactate levels. In the context exercise is more sensitive to physical exercise in biochemical and histological terms of gender submitted to tenotomy of the calcaneus tendon. Twelve adult Wistar rats were divided into three groups: Exercise, Injury and Injury + exercise. The animals were submitted to tenotomy of the calcaneus tendon and to the physical exercise protocol (forced swimming for 30min). The levels of lactate and glycemia before injury occurred 7 and 14 days after injury. A histological analysis was performed 14 days after the automatic coloring of the light and the autofluorescence of the collagen. Functional function was used for the functional analysis of the lesion at 7 and 14 days after injury. The analysis was performed using the ANOVA-1 test followed by the Tukey post-test, considering a significant p <0.05 with data expressed as mean ± standard deviation. The results showed a lower functional loss of the lesion + exercise group compared to the group Injury when compared to Exercise group. Functional analysis was performed in a structured way between the lesion + exercise group and the lesion group, characteristic of the healing process, differing from the exercise group. The analysis of autofluorescence colzing of which the group is less in the density groups of experiment. Lactate and glycemia values were not expressed between groups and days of analysis. In this way, we concluded the physical exercise to repair the calcaneus tendon in less functional time 7 and 14 days after the injury, and the maintenance of the collagen mesh in 14 days post-injury, despite presenting areas of degeneration in both groups that suffered injury. And by physical exercise protocol did not show effect of variation in the levels of lactate and glicemia in 7 and 14 days after the injury of the calcaneal tendon.