The complications of Hepatic Cirrhosis (HC) are the fifth cause of death in the world.
Hepatorenal Syndrome (HRS) is one of these complications and its presence greatly
decreases this prognosis. This study aims to investigate the occurrence of HRS
among cirrhotic patients admitted in a university hospital. It was a cross-sectional,
retrospective and descriptive study based on secondary data from medical records of
HC patients hospitalized in the last 5 years in the wards of a university hospital in the
northern region of the country. After filling out the standard protocol form, the data
were analyzed by distributing the groups according to the absence of renal injury
(GI), with non-HRS injury (GII) and with HRS injury (GIII). The Ethics Committee on
Research in Human Beings approved the present study. The study sample consisted
of 164 patients, 100 (60,9%) belonging to GI, 51 (31,09%) to GII and 13 (7,9%) to
GIII. In groups I and II there was a predominance of males (54% and 62%), but
women were more prevalent in G III, 61.5%, without statistical difference. The same
occurred with the mean age in years (56.33 x 61.21x 62.07), similar in all three
groups, despite the trend of lower age in GI. The most frequent etiologies in all
groups were hepatitis C, alcoholism and hepatitis B. When Child-Pugh was
classified, there was a predominance of Child C, in groups II and III (64.7% x 100%),
with statistical significance (p < 0.0001), as well as the period of hospitalization was
higher (p = 0.0093) in group II (27 days) than in GI (19.78 days) and G III (17.07
days). When the mortality was verified, there was a clear predominance of deaths in
G III (92.3%), than in GI (13%) and G II (45%), reaching meaningful significance (p <
0,0001).
It was concluded, therefore, that the demographic and etiologic data explored are
similar in the cirrhotic groups with or without renal lesion, however the patients with
HRS, interne with greater severity and present a high mortality rate.
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