Trabalho de Conclusão de Curso - Graduação

COVID-19:incidência, características clínicas e laboratoriais de pacientes hospitalizados com tromboembolismo venoso: uma experiência de três centros de assistência terciária numa cidade capital da amazônia oriental.

Background: The pandemic of COVID­19 presents itself, to date, as the greatest health challenge of this century. Central physiopathology involves an infectious respiratory disease caused by SARS­CoV­2 capable of causing cardiovascular complications in the most sever...

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Autor principal: NEGIDIO, Adson Kevin Cunha
Outros Autores: SILVA, Ester Almeida Carneiro Rodrigues da
Grau: Trabalho de Conclusão de Curso - Graduação
Publicado em: 2023
Assuntos:
Acesso em linha: https://bdm.ufpa.br:8443/jspui/handle/prefix/5575
Resumo:
Background: The pandemic of COVID­19 presents itself, to date, as the greatest health challenge of this century. Central physiopathology involves an infectious respiratory disease caused by SARS­CoV­2 capable of causing cardiovascular complications in the most severe cases, including thromboembolism. Objective: This study aims to characterize the clinical and laboratory profile of hospitalized patients with documented thrombosis/pulmonary thromboembolism during COVID­19 infection. Methods: Medical records of patients hospitalized in three tertiary care medical centers in the capital city of Pará, Brazil, with deep vein thrombosis or pulmonary thromboembolism diagnosed by imaging were reviewed. Relevant epidemiological, comorbidities, and laboratory data were analyzed. Results: The incidence of venous thromboembolism was 1.3%, ranging from 0.6% to 2.25% in the different centers. Mean values for age, C­reactive protein, D­dimer, body mass index, and length of stay were 46.35 years, 143.23 mg/l, 4.12 µg/ml, 27.65 kg/m², and 50.18 days, respectively. No significant correlations (p­value <0.05) were found between any of the variables studied and the presence of thrombosis or pulmonary thromboembolism. Conclusion: There seems to be no relationship between the presence of venous thromboembolism and the presence of some prevalent endocrine­metabolic comorbidities or laboratory patterns in COVID­19 infection. Individual risk factors may significantly influence the thrombotic and thromboembolic risk. Important limitations in data including the possibility of underdiagnosis and incomplete completion of medical records may confound the results. Some public health referral services need more infrastructural support. More studies should be conducted involving more accurate data.