Efeito do praziquantel sobre as variáveis sangüíneas de Colossoma macropomum Curvier, 1818 (Characidae: Serrasalminae) e sua eficiência como anti-helmíntico no controle de parasitas monogenóides (Plathyhelminthes: Monogenoidea)
In order to contribute with research on the use of chemical therapeutics in aquaculture, especially involving native fish species such as the tambaqui, Colossoma macropomum, the present study aimed to evaluate the antihelmintic praziquantel toxic effects on tambaqui through hematological analysis...
| Autor principal: | Maciel, Patricia Oliveira |
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| Grau: | Dissertação |
| Idioma: | por |
| Publicado em: |
Instituto Nacional de Pesquisas da Amazônia - INPA
2020
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| Assuntos: | |
| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/11351 http://lattes.cnpq.br/5589512332249547 |
| Resumo: |
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In order to contribute with research on the use of chemical therapeutics in aquaculture,
especially involving native fish species such as the tambaqui, Colossoma macropomum, the
present study aimed to evaluate the antihelmintic praziquantel toxic effects on tambaqui
through hematological analysis (Chapter 1) and, complementarily, to evaluate its efficacy to
control monogenea parasites (Chapter 2). In Chapter 1, bath of 3.12; 6.25; 12.5; 25 and 50 mg
of praziquantel/L during 0.5; 1 and 24 hours of exposure were tested. Among the blood
parameters evaluated, hemoglobin concentration and mean corpuscular hemoglobin decreased
in fish exposed during 24 hr and hyperglycemia was observed on those exposed to the highest
concentrations of praziquantel (25 and 50 mg/L) in all bath duration. Results suggest that
praziquantel concentrations of 25 and 50 mg/L affect tambaqui homeostasis, regardless the
exposing time, and may cause fish mortality. Besides, this study corroborate with the
hypothesis that tambaqui aquatic surface respiration (ASR), with the formation of mouth lips,
may be stimulated by the reduction of tissue oxygen concentration (hypoxemia), regardless
water dissolved oxygen concentration. In Chapter 2, five praziquantel concentrations were
tested: 0; 6.25; 12.5; 25 and 35 mg/L in 24 hr baths and blood parameters and fish parasite
load were evaluated. In most treatments efficacy was under 60%, except for the treatment
with 12.5 mg/L which resulted in 61.8% efficacy. This study indicated that lower praziquantel
concentrations were more efficient in controlling the parasites and high concentration of the
product induced fish leukocyte alterations comparable to stress, such as lymphopenia,
monocytosis, neutrophylia, and hyperglycemia. |