Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity

Nascimento, Ozanildo V; Boleti, Ana P.A; Yuyama, Lucia Kiyoko Ozaki; Lima, Emerson Silva

Artigo

Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity

Amazonian Camu-camu fruit (Myrciaria dubia HBK Mc Vaugh) has attracted interest from food and cosmetics industries because of its rich content of vitamin C, flavonoids and anthocyanins. The goal of this study was investigates the antiobesity action of the ingestion of the Camu-camu pulp in a rat mod...

ver descrição completa

Autor principal:	Nascimento, Ozanildo V
Outros Autores:	Boleti, Ana P.A, Yuyama, Lucia Kiyoko Ozaki, Lima, Emerson Silva
Grau:	Artigo
Idioma:	English
Publicado em:	Anais da Academia Brasileira de Ciências 2020
Assuntos:	Amazonian Fruit Flavonoids Lipid Profile Myrciaria Dubia Obesity Fruto Da Amazônia Flavonoides Perfil Lipídico Myrciaria Dubia Obesidade
Acesso em linha:	https://repositorio.inpa.gov.br/handle/1/13117

id	oai:repositorio:1-13117
recordtype	dspace
spelling	oai:repositorio:1-13117 Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity Nascimento, Ozanildo V Boleti, Ana P.A Yuyama, Lucia Kiyoko Ozaki Lima, Emerson Silva Amazonian Fruit Flavonoids Lipid Profile Myrciaria Dubia Obesity Fruto Da Amazônia Flavonoides Perfil Lipídico Myrciaria Dubia Obesidade Amazonian Camu-camu fruit (Myrciaria dubia HBK Mc Vaugh) has attracted interest from food and cosmetics industries because of its rich content of vitamin C, flavonoids and anthocyanins. The goal of this study was investigates the antiobesity action of the ingestion of the Camu-camu pulp in a rat model of diet-induced obesity. Wistar rats with obesity induced by subcutaneous injection of monosodium glutamate receiving diet ad libitum. The rats were divided in two groupsan experimental group that ingested 25 mL/day of Camu-camu pulp (CCG) and a non treated group (CG). After 12 weeks, the animals were sacrificed. Blood, liver, heart, white adipose tissues were collected and weighted, biochemical and inflammatory profiles were determinate as well. Animals that received the pulp of Camu-camu reduced their weights of the fat in white adipose tissues, glucose, total cholesterol, triglycerides, LDL-c and insulin blood levels. There was an increase in HDL-c levels. No change was observed in inflammatory markers and liver enzymes. Camu-camu pulp was able to improve the biochemical profile of obesity in rats suggesting that this Amazonian fruit can be further used such a functional food ingredient in control of chronic diseases linked to obesity. O fruto Camu-camu da amazônia (Myrciaria dubia HBK Mc Vaugh) apresenta um interesse atrativo na alimentação e industria de cosméticos devido ao rico conteúdo de Vitamina C, flavonoides e antocianinas. O objetivo deste estudo foi investigar a ação antiobesidade da ingestão da polpa de Camu-camu em modelo de ratos obesos. Ratos Wistars foram induzidos a obesidade pela injeção subcutânea de glutamato monossódico recebendo dieta ad libitum. Os ratos foram divididos em dois grupos. Um grupo experimental, que ingeriram 25 mL/dia de polpa de Camu-camu (CCG) e um grupo não tratado (CG). Após 12 semanas, os animais foram sacrificados. Sangue, fígado, coração e tecido adiposo foram coletados e pesados, assim como determinado os perfis bioquímicos e inflamatórios. Animais que receberam a polpa de Camu-camu reduziram o peso do tecido adiposo, os níveis plasmáticos de glicose, colesterol total, trigliceridios, LDL-c e níveis de insulina no sangue. Houve um aumento nos níveis de HDL-c. Nenhuma mudança foi observada nos marcadores inflamatórios e enzimas do fígado. A polpa de Camu-camu foi capaz de melhorar o perfil bioquímico da obesidade em ratos, sugerindo que este fruto da Amazônia pode ser futuramente utilizado como um ingrediente alimentar funcional no controle de doenças crônicas ligadas a obesidade. 2020-04-24T15:14:39Z 2020-04-24T15:14:39Z 2013 Artigo https://repositorio.inpa.gov.br/handle/1/13117 10.1590/S0001-37652013005000001 en Volume 85, Número 1, Pags. 355-363 Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ application/pdf Anais da Academia Brasileira de Ciências
institution	Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional
collection	INPA-RI
language	English
topic	Amazonian Fruit Flavonoids Lipid Profile Myrciaria Dubia Obesity Fruto Da Amazônia Flavonoides Perfil Lipídico Myrciaria Dubia Obesidade
spellingShingle	Amazonian Fruit Flavonoids Lipid Profile Myrciaria Dubia Obesity Fruto Da Amazônia Flavonoides Perfil Lipídico Myrciaria Dubia Obesidade Nascimento, Ozanildo V Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
topic_facet	Amazonian Fruit Flavonoids Lipid Profile Myrciaria Dubia Obesity Fruto Da Amazônia Flavonoides Perfil Lipídico Myrciaria Dubia Obesidade
description	Amazonian Camu-camu fruit (Myrciaria dubia HBK Mc Vaugh) has attracted interest from food and cosmetics industries because of its rich content of vitamin C, flavonoids and anthocyanins. The goal of this study was investigates the antiobesity action of the ingestion of the Camu-camu pulp in a rat model of diet-induced obesity. Wistar rats with obesity induced by subcutaneous injection of monosodium glutamate receiving diet ad libitum. The rats were divided in two groupsan experimental group that ingested 25 mL/day of Camu-camu pulp (CCG) and a non treated group (CG). After 12 weeks, the animals were sacrificed. Blood, liver, heart, white adipose tissues were collected and weighted, biochemical and inflammatory profiles were determinate as well. Animals that received the pulp of Camu-camu reduced their weights of the fat in white adipose tissues, glucose, total cholesterol, triglycerides, LDL-c and insulin blood levels. There was an increase in HDL-c levels. No change was observed in inflammatory markers and liver enzymes. Camu-camu pulp was able to improve the biochemical profile of obesity in rats suggesting that this Amazonian fruit can be further used such a functional food ingredient in control of chronic diseases linked to obesity.
format	Artigo
author	Nascimento, Ozanildo V
author2	Boleti, Ana P.A Yuyama, Lucia Kiyoko Ozaki Lima, Emerson Silva
author2Str	Boleti, Ana P.A Yuyama, Lucia Kiyoko Ozaki Lima, Emerson Silva
title	Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
title_short	Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
title_full	Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
title_fullStr	Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
title_full_unstemmed	Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity
title_sort	effects of diet supplementation with camu-camu (myrciaria dubia hbk mcvaugh) fruit in a rat model of diet-induced obesity
publisher	Anais da Academia Brasileira de Ciências
publishDate	2020
url	https://repositorio.inpa.gov.br/handle/1/13117
_version_	1787141747020660736
score	11.755432

Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity

Registros relacionados