Artigo

Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos

Vitamin A deficiency is a serious public health problem in the world. In Brazilian Amazonia, some native fruits may be pointed as good sources of this vitamin, provided their abundant pro-vitamin A present high bioavailability. The present study evaluated the bioavailability of carotenoids from Buri...

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Autor principal: Yuyama, Lucia Kiyoko Ozaki
Outros Autores: Yonekura, Lina, Aguiar, Jaime Paiva Lopes, Sousa, Risonilce F S
Grau: Artigo
Idioma: pt_BR
Publicado em: Acta Amazonica 2020
Assuntos:
Carotenoids
Buriti Fruit
Bioavailability
Rats
Carotenóides
Buriti
Biodisponibilidade
Ratos
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/13221
id oai:repositorio:1-13221
recordtype dspace
spelling oai:repositorio:1-13221 Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos Bioavailability of Carotenoids from Buriti (Mauritia flexuosa L.) in Rats Yuyama, Lucia Kiyoko Ozaki Yonekura, Lina Aguiar, Jaime Paiva Lopes Sousa, Risonilce F S Carotenoids Buriti Fruit Bioavailability Rats Carotenóides Buriti Biodisponibilidade Ratos Vitamin A deficiency is a serious public health problem in the world. In Brazilian Amazonia, some native fruits may be pointed as good sources of this vitamin, provided their abundant pro-vitamin A present high bioavailability. The present study evaluated the bioavailability of carotenoids from Buriti (Mauritia flexuosa L.) in rats. Forty eight recently weaned male Wistar rats (Rattus novergicus, var. albinus, Rodentia: Mammalia), mean weight 33.8 ± 1.7g, were separated into five groups as follows: Deficient, Control 1200, Control 2400, Buriti 1200 and Buriti 2400. All diets were prepared according to the Committee on Laboratory Animal Diets (1993). After 28 days, the liver and plasma contents of all animals were analysed for Vitamin A and carotene levels. The lowest plasmatic and hepatic levels of Vitamin A were observed in the Deficient Group, while hepatic Vitamin A reserves of the animals from the Buriti 1200 and Buriti 2400 Groups were significantly higher than the Control 1200 and Control 2400 Groups respectively. The results of the study showed that buriti is a highly bioavailable source of pro-vitamin A, with a relative efficiency of 254.6% (1200ER/Kg diet) and 179.4% (2400/Kg diet) when compared with the respective control groups, indicating a higher carotenoids bioavailability, near recommended doses. Considerando a magnitude da hipovitaminose A como problema de saúde pública no mundo e a disponibilidade de frutos ricos em pró-vitamina A na região Amazônica, determinou-se a biodisponibilidade dos carotenóides do Buriti (Mauritia flexuosa L.) em ratos. Quarenta e oito ratos machos da linhagem Wistar (Rattus novergicus, var. albinus, RodentiaMammalia) recém-desmamados, com peso médio inicial de 33,8 ± 1,7g, foram distribuídos em cinco grupos, ou seja, GruposDeficiente, Controle 1200, Controle 2400, Buriti 1200 e Buriti 2400. As rações foram elaboradas de acordo com a recomendação do Committee on Laboratory Animal Diets (1993). Após o período experimental de 28 dias, todos os animais foram sacrificados para a determinação de vitamina A e caroteno no plasma e no fígado. A menor concentração de vitamina A hepática e plasmática foi observada no Grupo Deficiente. Por sua vez, as reservas hepáticas de vitamina A dos animais dos grupos Buriti 1200 e 2400 foram significativamente superiores quando comparados com os grupos Controle 1200 e 2400, respectivamente. Os resultados desse estudo demonstraram ser o buriti uma fonte de pró-vitamina A altamente biodisponível, com eficiência relativa de 254,6% (1200ER/Kg ração) e 179,4% (2400 ER/Kg ração) quando comparado com os respectivos grupos controle, indicando a maior biodisponibilidade dos carotenóides em doses próximas à recomendada. 2020-04-24T15:16:41Z 2020-04-24T15:16:41Z 1998 Artigo https://repositorio.inpa.gov.br/handle/1/13221 10.1590/1809-43921998284415 pt_BR Volume 28, Número 4, Pags. 409-409 Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ application/pdf Acta Amazonica
institution Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional
collection INPA-RI
language pt_BR
topic Carotenoids
Buriti Fruit
Bioavailability
Rats
Carotenóides
Buriti
Biodisponibilidade
Ratos
spellingShingle Carotenoids
Buriti Fruit
Bioavailability
Rats
Carotenóides
Buriti
Biodisponibilidade
Ratos
Yuyama, Lucia Kiyoko Ozaki
Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos
topic_facet Carotenoids
Buriti Fruit
Bioavailability
Rats
Carotenóides
Buriti
Biodisponibilidade
Ratos
description Vitamin A deficiency is a serious public health problem in the world. In Brazilian Amazonia, some native fruits may be pointed as good sources of this vitamin, provided their abundant pro-vitamin A present high bioavailability. The present study evaluated the bioavailability of carotenoids from Buriti (Mauritia flexuosa L.) in rats. Forty eight recently weaned male Wistar rats (Rattus novergicus, var. albinus, Rodentia: Mammalia), mean weight 33.8 ± 1.7g, were separated into five groups as follows: Deficient, Control 1200, Control 2400, Buriti 1200 and Buriti 2400. All diets were prepared according to the Committee on Laboratory Animal Diets (1993). After 28 days, the liver and plasma contents of all animals were analysed for Vitamin A and carotene levels. The lowest plasmatic and hepatic levels of Vitamin A were observed in the Deficient Group, while hepatic Vitamin A reserves of the animals from the Buriti 1200 and Buriti 2400 Groups were significantly higher than the Control 1200 and Control 2400 Groups respectively. The results of the study showed that buriti is a highly bioavailable source of pro-vitamin A, with a relative efficiency of 254.6% (1200ER/Kg diet) and 179.4% (2400/Kg diet) when compared with the respective control groups, indicating a higher carotenoids bioavailability, near recommended doses.
format Artigo
author Yuyama, Lucia Kiyoko Ozaki
author2 Yonekura, Lina
Aguiar, Jaime Paiva Lopes
Sousa, Risonilce F S
author2Str Yonekura, Lina
Aguiar, Jaime Paiva Lopes
Sousa, Risonilce F S
title Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos
title_short Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos
title_full Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos
title_fullStr Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos
title_full_unstemmed Biodisponibilidade dos Carotenóides do Buriti (Mauritia flexuosa l.) em Ratos
title_sort biodisponibilidade dos carotenóides do buriti (mauritia flexuosa l.) em ratos
publisher Acta Amazonica
publishDate 2020
url https://repositorio.inpa.gov.br/handle/1/13221
_version_ 1787143697800888320
score 11.653393

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