Artigo

Interaction between smoking and HLA-DRB1*04 gene is associated with a high cardiovascular risk in Brazilian Amazon patients with rheumatoid arthritis

Background: Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints that affects approximately 1% of the population worldwide. The HLA-DRB1 gene locus plays a major role in genetic susceptibility to RA, a condition that has been associated with a high c...

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Autor principal: Boechat, Narjara de Oliveira
Outros Autores: Ogusku, Maurício Morishi, Boechat, Antonio Luiz, Sadahiro, Aya
Grau: Artigo
Idioma: English
Publicado em: PLoS ONE 2020
Assuntos:
Epitope
Hla Drb1 Antigen
Hla Drb5 Antigen
Adult
Allele
Cardiovascular Risk
Case Control Study
Controlled Study
Disease Activity
Female
Gene
Genetic Association
Genetic Risk
Genetic Susceptibility
Genotype-environment Interaction
High Risk Population
Hla Drb1 Gene
Hla Drb5 Gene
Human
Major Clinical Study
Male
Arthritis, Rheumatoid
Risk Assessment
Smoking Habit
Trend Study
Adult
Arthritis, Rheumatoid
Brasil
Cardiovascular Diseases
Female
Genotype
Hla-drb1 Chains
Humans
Logistic Models
Male
Middle Aged
Risk
Smoking
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/14726

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