Artigo

Dibutyl phthalate induced testicular dysgenesis originates after seminiferous cord formation in rats

Administration of dibutyl phthalate (DBP) to pregnant rats causes reproductive disorders in male offspring, resulting from suppression of intratesticular testosterone, and is used as a model for human testicular dysgenesis syndrome (TDS). DBP exposure in pregnancy induces focal dysgenetic areas in f...

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Autor principal: Lara, Nathália L.M.
Outros Autores: van den Driesche, Sander, MacPherson, Sheila A., França, Luiz Renato de, Sharpe, Richard M.
Grau: Artigo
Idioma: English
Publicado em: Scientific Reports 2020
Assuntos:
Phthalic Acid Dibutyl Ester
Animals
Chemically Induced
Disease Model
Drug Effect
Female
Fetus
Gonadal Dysgenesis
Growth, Development And Aging
Human
Leydig Cell
Male
Pathology
Pathophysiology
Pregnancy
Prenatal Exposure
Rat
Seminiferous Tubule
Sex Differentiation
Testis
Testis Disease
Wistar Rat
Animal
Dibutyl Phthalate
Disease Models, Animals
Female
Fetus
Gonadal Dysgenesis
Humans
Leydig Cells
Male
Pregnancy
Prenatal Exposure Delayed Effects
Rats
Rats, Wistar
Seminiferous Tubules
Sex Differentiation
Testicular Diseases
Testis
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/15217

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