Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis
An adult male Amazonian manatee Trichechus inunguis under human care presented with 3 circular cutaneous lesions on the dorsal aspect of the rostrum and between the nostrils (plenum). Initially these lesions were superficial, hypopigmented, without warmth and non-painful. Microbiological cultures of...
| Autor principal: | Reisfeld, Laura |
|---|---|
| Outros Autores: | Ikuta, C. Y., Ippolito, Laura, Silvatti, Bruna, Neto, Josè Soares Ferreira, Catão-Dias, José Luiz, Weber Rosas, Fernando Cesar, D'Affonsêca Neto, José Anselmo, Silva, Vera Maria Ferreira da |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Diseases of Aquatic Organisms
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/15649 |
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oai:repositorio:1-15649 |
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oai:repositorio:1-15649 Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis Reisfeld, Laura Ikuta, C. Y. Ippolito, Laura Silvatti, Bruna Neto, Josè Soares Ferreira Catão-Dias, José Luiz Weber Rosas, Fernando Cesar D'Affonsêca Neto, José Anselmo Silva, Vera Maria Ferreira da Adult Antibiotics Bacterial Disease Bacterium Captive Population Histopathology Marine Mammal Pathogen Temperature Effect Animalsia Bacilli (class) Candida Corynebacterineae Mammalia Mycobacterium Mycobacterium Abscessus Mycobacterium Fortuitum Pseudomonas Aeruginosa Trichechus Inunguis Antiinfective Agent Ciprofloxacin Clarithromycin Animals Atypical Mycobacteriosis Bacterial Skin Disease Case Report Isolation And Purification Male Microbiology Mycobacterium Fortuitum Pathology Trichechus Inunguis Veterinary Animal Anti-bacterial Agents Ciprofloxacin Clarithromycin Male Mycobacterium Fortuitum Mycobacterium Infections, Nontuberculous Skin Diseases, Bacterial Trichechus Inunguis An adult male Amazonian manatee Trichechus inunguis under human care presented with 3 circular cutaneous lesions on the dorsal aspect of the rostrum and between the nostrils (plenum). Initially these lesions were superficial, hypopigmented, without warmth and non-painful. Microbiological cultures of skin swabs isolated Candida sp. and Pseudomonas aeruginosa, and topical treatment with antiseptic, antifungal, anti-inflammatory and antibiotic medication was instituted. This treatment strategy did not lead to any clinical improvement, and after 6 mo, the lesions progressed to a confluent abscess (5.0 × 3.0 cm) with increased temperature and obvious discomfort on palpation. An impression smear of a cutaneous biopsy was submitted for Ziehl-Neelsen staining and after detection of acid-fast bacilli, the cutaneous biopsy and a swab from the lesion were sent for histopathology, culture and sensitivity testing. After 5 d of incubation and through PCR-restriction analysis of the isolates, Mycobacterium fortuitum and M. abscessus were identified. Sensitivity testing indicated that the isolates were susceptible to ciprofloxacin and clarithromycin, and after draining of the lesion and administration of systemic antibiotic treatment, there was rapid clinical improvement. This report describes non-healing lesions in an aquatic animal and illustrates the importance of evaluating the presence of non-tuberculous mycobacteria, opportunistic pathogens which are ubiquitous in the aquatic environment, in protracted, non-responsive cases. We also highlight the importance of a correct diagnosis and treatment approach, and we review concerns that these bacteria are zoonotic agents and are frequently resistant to conventional antibiotics. © Inter-Research 2018. 2020-05-15T19:22:52Z 2020-05-15T19:22:52Z 2018 Artigo https://repositorio.inpa.gov.br/handle/1/15649 10.3354/dao03196 en Volume 127, Número 3, Pags. 231-236 Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ application/pdf Diseases of Aquatic Organisms |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Adult Antibiotics Bacterial Disease Bacterium Captive Population Histopathology Marine Mammal Pathogen Temperature Effect Animalsia Bacilli (class) Candida Corynebacterineae Mammalia Mycobacterium Mycobacterium Abscessus Mycobacterium Fortuitum Pseudomonas Aeruginosa Trichechus Inunguis Antiinfective Agent Ciprofloxacin Clarithromycin Animals Atypical Mycobacteriosis Bacterial Skin Disease Case Report Isolation And Purification Male Microbiology Mycobacterium Fortuitum Pathology Trichechus Inunguis Veterinary Animal Anti-bacterial Agents Ciprofloxacin Clarithromycin Male Mycobacterium Fortuitum Mycobacterium Infections, Nontuberculous Skin Diseases, Bacterial Trichechus Inunguis |
| spellingShingle |
Adult Antibiotics Bacterial Disease Bacterium Captive Population Histopathology Marine Mammal Pathogen Temperature Effect Animalsia Bacilli (class) Candida Corynebacterineae Mammalia Mycobacterium Mycobacterium Abscessus Mycobacterium Fortuitum Pseudomonas Aeruginosa Trichechus Inunguis Antiinfective Agent Ciprofloxacin Clarithromycin Animals Atypical Mycobacteriosis Bacterial Skin Disease Case Report Isolation And Purification Male Microbiology Mycobacterium Fortuitum Pathology Trichechus Inunguis Veterinary Animal Anti-bacterial Agents Ciprofloxacin Clarithromycin Male Mycobacterium Fortuitum Mycobacterium Infections, Nontuberculous Skin Diseases, Bacterial Trichechus Inunguis Reisfeld, Laura Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis |
| topic_facet |
Adult Antibiotics Bacterial Disease Bacterium Captive Population Histopathology Marine Mammal Pathogen Temperature Effect Animalsia Bacilli (class) Candida Corynebacterineae Mammalia Mycobacterium Mycobacterium Abscessus Mycobacterium Fortuitum Pseudomonas Aeruginosa Trichechus Inunguis Antiinfective Agent Ciprofloxacin Clarithromycin Animals Atypical Mycobacteriosis Bacterial Skin Disease Case Report Isolation And Purification Male Microbiology Mycobacterium Fortuitum Pathology Trichechus Inunguis Veterinary Animal Anti-bacterial Agents Ciprofloxacin Clarithromycin Male Mycobacterium Fortuitum Mycobacterium Infections, Nontuberculous Skin Diseases, Bacterial Trichechus Inunguis |
| description |
An adult male Amazonian manatee Trichechus inunguis under human care presented with 3 circular cutaneous lesions on the dorsal aspect of the rostrum and between the nostrils (plenum). Initially these lesions were superficial, hypopigmented, without warmth and non-painful. Microbiological cultures of skin swabs isolated Candida sp. and Pseudomonas aeruginosa, and topical treatment with antiseptic, antifungal, anti-inflammatory and antibiotic medication was instituted. This treatment strategy did not lead to any clinical improvement, and after 6 mo, the lesions progressed to a confluent abscess (5.0 × 3.0 cm) with increased temperature and obvious discomfort on palpation. An impression smear of a cutaneous biopsy was submitted for Ziehl-Neelsen staining and after detection of acid-fast bacilli, the cutaneous biopsy and a swab from the lesion were sent for histopathology, culture and sensitivity testing. After 5 d of incubation and through PCR-restriction analysis of the isolates, Mycobacterium fortuitum and M. abscessus were identified. Sensitivity testing indicated that the isolates were susceptible to ciprofloxacin and clarithromycin, and after draining of the lesion and administration of systemic antibiotic treatment, there was rapid clinical improvement. This report describes non-healing lesions in an aquatic animal and illustrates the importance of evaluating the presence of non-tuberculous mycobacteria, opportunistic pathogens which are ubiquitous in the aquatic environment, in protracted, non-responsive cases. We also highlight the importance of a correct diagnosis and treatment approach, and we review concerns that these bacteria are zoonotic agents and are frequently resistant to conventional antibiotics. © Inter-Research 2018. |
| format |
Artigo |
| author |
Reisfeld, Laura |
| author2 |
Ikuta, C. Y. Ippolito, Laura Silvatti, Bruna Neto, Josè Soares Ferreira Catão-Dias, José Luiz Weber Rosas, Fernando Cesar D'Affonsêca Neto, José Anselmo Silva, Vera Maria Ferreira da |
| author2Str |
Ikuta, C. Y. Ippolito, Laura Silvatti, Bruna Neto, Josè Soares Ferreira Catão-Dias, José Luiz Weber Rosas, Fernando Cesar D'Affonsêca Neto, José Anselmo Silva, Vera Maria Ferreira da |
| title |
Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis |
| title_short |
Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis |
| title_full |
Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis |
| title_fullStr |
Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis |
| title_full_unstemmed |
Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis |
| title_sort |
cutaneous mycobacteriosis in a captive amazonian manatee trichechus inunguis |
| publisher |
Diseases of Aquatic Organisms |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/15649 |
| _version_ |
1787143916436324352 |
| score |
11.755432 |