Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats.
Studies with fruit and vegetables rich in dietary fber have shown lowering effects on the blood concentrations of total cholesterol (TC), acting preventively against hypercholesterolemia. The aim of this study was to analyze the chemical composition of cocona and evaluate the effect of the consumpti...
| Autor principal: | Maia, Jeniffer Resende Patrocínio |
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| Outros Autores: | Schwertz, Maíra Cássia, Sousa, R. F S, Aguiar, Jaime Paiva Lopes, Lima, Emerson Silva |
| Grau: | Artigo |
| Idioma: | pt_BR |
| Publicado em: |
Revista Brasileira de Plantas Medicinais
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/15933 |
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oai:repositorio:1-15933 |
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oai:repositorio:1-15933 Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. Efeito hipolipemiante da suplementação dietética com a farinha do cubiu (solanum sessiliforum dunal) em ratos hipercolesterolêmicos Maia, Jeniffer Resende Patrocínio Schwertz, Maíra Cássia Sousa, R. F S Aguiar, Jaime Paiva Lopes Lima, Emerson Silva Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum Studies with fruit and vegetables rich in dietary fber have shown lowering effects on the blood concentrations of total cholesterol (TC), acting preventively against hypercholesterolemia. The aim of this study was to analyze the chemical composition of cocona and evaluate the effect of the consumption of cocona four on lipemia of Wistar rats with hypercholesterolemia. Eight animals were used for each treatment, in 7 groups: control; 3 experimental groups with 5%, 25% and 50% of the recommended fber (AIN-93) from cocona four; 3 groups per feeding with pectin and cellulose as source of dietary fber, in the same proportions of the experimental groups. At the end of the assay, we verifed that there were not signifcant variations in the consumption of the animals and the body weight during the experiment. Treatments with cocna four were responsible for reducing the concentrations of total cholesterol (-21.6%), LDL-c (-56.8%), increasing the excretion of fecal cholesterol (+116%) and lowering the liver cholesterol (-32.1%). None of the treatments signifcantly altered the triglyceride concentrations. Treatments using pectin and cellulose show results similar to cocona. The observed results can be used in further studies aimed at the biotechnological exploitation of this fruit. © 2015, Instituto de Biociencias. All rights reserved. 2020-05-20T19:08:46Z 2020-05-20T19:08:46Z 2015 Artigo https://repositorio.inpa.gov.br/handle/1/15933 10.1590/1983-084X/11_163 pt_BR Volume 17, Número 1, Pags. 112-119 Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ application/pdf Revista Brasileira de Plantas Medicinais |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
pt_BR |
| topic |
Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum |
| spellingShingle |
Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum Maia, Jeniffer Resende Patrocínio Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| topic_facet |
Antilipemic Agent Cellulose Cholesterol Low Density Lipoprotein Cholesterol Pectin Animals Model Chemical Composition Controlled Study Diet Supplementation Dietary Fiber Flour Fruit Hypercholesterolemia Nonhuman Rat Solanum Solanum Sessiliflorum Animalsia Rattus Rattus Norvegicus Solanum |
| description |
Studies with fruit and vegetables rich in dietary fber have shown lowering effects on the blood concentrations of total cholesterol (TC), acting preventively against hypercholesterolemia. The aim of this study was to analyze the chemical composition of cocona and evaluate the effect of the consumption of cocona four on lipemia of Wistar rats with hypercholesterolemia. Eight animals were used for each treatment, in 7 groups: control; 3 experimental groups with 5%, 25% and 50% of the recommended fber (AIN-93) from cocona four; 3 groups per feeding with pectin and cellulose as source of dietary fber, in the same proportions of the experimental groups. At the end of the assay, we verifed that there were not signifcant variations in the consumption of the animals and the body weight during the experiment. Treatments with cocna four were responsible for reducing the concentrations of total cholesterol (-21.6%), LDL-c (-56.8%), increasing the excretion of fecal cholesterol (+116%) and lowering the liver cholesterol (-32.1%). None of the treatments signifcantly altered the triglyceride concentrations. Treatments using pectin and cellulose show results similar to cocona. The observed results can be used in further studies aimed at the biotechnological exploitation of this fruit. © 2015, Instituto de Biociencias. All rights reserved. |
| format |
Artigo |
| author |
Maia, Jeniffer Resende Patrocínio |
| author2 |
Schwertz, Maíra Cássia Sousa, R. F S Aguiar, Jaime Paiva Lopes Lima, Emerson Silva |
| author2Str |
Schwertz, Maíra Cássia Sousa, R. F S Aguiar, Jaime Paiva Lopes Lima, Emerson Silva |
| title |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| title_short |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| title_full |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| title_fullStr |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| title_full_unstemmed |
Hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| title_sort |
hypolipidemic effect of diet supplementation with cocona (solanum sessiliforum dunal) four in hypercholesterolemic rats. |
| publisher |
Revista Brasileira de Plantas Medicinais |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/15933 |
| _version_ |
1787142591860441088 |
| score |
11.653393 |