Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil
The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multid...
| Autor principal: | Mejía, Matilde Del Carmen Contreras |
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| Outros Autores: | dos Santos, Maísa Porto, Silva, George Allan Villarouco da, Motta-Passos, Isabella da, Naveca, Felipe Gomes, Cunha, Maria Coelho Graça Souza, Moraes, Milton Ozório, Paula, Lúcia de |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Journal of Clinical Microbiology
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/16019 |
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oai:repositorio:1-16019 |
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oai:repositorio:1-16019 Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil Mejía, Matilde Del Carmen Contreras dos Santos, Maísa Porto Silva, George Allan Villarouco da Motta-Passos, Isabella da Naveca, Felipe Gomes Cunha, Maria Coelho Graça Souza Moraes, Milton Ozório Paula, Lúcia de Rifampicin Antiinfective Agent Bacterial Protein Rifampicin Antibiotic Resistance Bacterial Gene Bacterial Strain Brasil Dna Sequence Folp1 Gene Polymorphism, Genetic Gyra Gene Human Human Tissue Leprosy Multidrug Resistance Mycobacterium Leprae Nonhuman Nucleotide Sequence Rpob Gene Drug Effects Female Genetics Isolation And Purification Leprosy Male Microbiology Mycobacterium Leprae Anti-bacterial Agents Bacterial Proteins Brasil Drug Resistance, Bacterial Female Humans Leprosy Male Mycobacterium Leprae Polymorphism, Genetic Rifampin The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance. Copyright © 2014, American Society for Microbiology. All Rights Reserved. 2020-05-21T21:56:30Z 2020-05-21T21:56:30Z 2014 Artigo https://repositorio.inpa.gov.br/handle/1/16019 10.1128/JCM.01688-14 en Volume 52, Número 12, Pags. 4359-4360 Attribution-NonCommercial-NoDerivs 3.0 Brazil http://creativecommons.org/licenses/by-nc-nd/3.0/br/ application/pdf Journal of Clinical Microbiology |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Rifampicin Antiinfective Agent Bacterial Protein Rifampicin Antibiotic Resistance Bacterial Gene Bacterial Strain Brasil Dna Sequence Folp1 Gene Polymorphism, Genetic Gyra Gene Human Human Tissue Leprosy Multidrug Resistance Mycobacterium Leprae Nonhuman Nucleotide Sequence Rpob Gene Drug Effects Female Genetics Isolation And Purification Leprosy Male Microbiology Mycobacterium Leprae Anti-bacterial Agents Bacterial Proteins Brasil Drug Resistance, Bacterial Female Humans Leprosy Male Mycobacterium Leprae Polymorphism, Genetic Rifampin |
| spellingShingle |
Rifampicin Antiinfective Agent Bacterial Protein Rifampicin Antibiotic Resistance Bacterial Gene Bacterial Strain Brasil Dna Sequence Folp1 Gene Polymorphism, Genetic Gyra Gene Human Human Tissue Leprosy Multidrug Resistance Mycobacterium Leprae Nonhuman Nucleotide Sequence Rpob Gene Drug Effects Female Genetics Isolation And Purification Leprosy Male Microbiology Mycobacterium Leprae Anti-bacterial Agents Bacterial Proteins Brasil Drug Resistance, Bacterial Female Humans Leprosy Male Mycobacterium Leprae Polymorphism, Genetic Rifampin Mejía, Matilde Del Carmen Contreras Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| topic_facet |
Rifampicin Antiinfective Agent Bacterial Protein Rifampicin Antibiotic Resistance Bacterial Gene Bacterial Strain Brasil Dna Sequence Folp1 Gene Polymorphism, Genetic Gyra Gene Human Human Tissue Leprosy Multidrug Resistance Mycobacterium Leprae Nonhuman Nucleotide Sequence Rpob Gene Drug Effects Female Genetics Isolation And Purification Leprosy Male Microbiology Mycobacterium Leprae Anti-bacterial Agents Bacterial Proteins Brasil Drug Resistance, Bacterial Female Humans Leprosy Male Mycobacterium Leprae Polymorphism, Genetic Rifampin |
| description |
The aim of this study was to identify polymorphisms in the folp1, gyrA, and rpoB genes in leprosy patients treated in Amazonas State, Brazil. Among 197 slit-skin smear samples from untreated or relapsed patients, we found three cases of primary resistance to rifampin and one confirmed case of multidrug resistance. Copyright © 2014, American Society for Microbiology. All Rights Reserved. |
| format |
Artigo |
| author |
Mejía, Matilde Del Carmen Contreras |
| author2 |
dos Santos, Maísa Porto Silva, George Allan Villarouco da Motta-Passos, Isabella da Naveca, Felipe Gomes Cunha, Maria Coelho Graça Souza Moraes, Milton Ozório Paula, Lúcia de |
| author2Str |
dos Santos, Maísa Porto Silva, George Allan Villarouco da Motta-Passos, Isabella da Naveca, Felipe Gomes Cunha, Maria Coelho Graça Souza Moraes, Milton Ozório Paula, Lúcia de |
| title |
Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| title_short |
Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| title_full |
Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| title_fullStr |
Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| title_full_unstemmed |
Identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in Amazonas State, Brazil |
| title_sort |
identification of primary drug resistance to rifampin in mycobacterium leprae strains from leprosy patients in amazonas state, brazil |
| publisher |
Journal of Clinical Microbiology |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/16019 |
| _version_ |
1787143337741910016 |
| score |
11.755432 |