Artigo

Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the development of experimental arthritis

Intracellular pattern recognition receptors such as the nucleotide-binding oligomerization domain (NOD)-like receptors family members are key for innate immune recognition of microbial infection and may play important roles in the development of inflammatory diseases, including rheumatic diseases. I...

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Autor principal: Manfredo Vieira, Silvio
Outros Autores: Cunha, Thiago Mattar, França, Rafael Freitas de Oliveira, Pinto, Larissa Garcia, Talbot, Jhimmy, Turato, Walter Miguel, Lemos, Henrique Paula, Lima, Jonilson Berlink, Verri, Waldiceu A., Almeida, Sërgio C.L., Ferreira, Seérgio Henrique, Louzada-Jünior, Paulo, Zamboni, Darío Simões, Cunha, Fernando Queiroz
Grau: Artigo
Idioma: English
Publicado em: Journal of Immunology 2020
Assuntos:
Caspase Recruitment Domain Protein 15
Caspase Recruitment Domain Protein 4
Cd4 Antigen
Cxcl1 Chemokine
Interleukin-17
Interleukin-1beta
Interleukin-23
Interleukin-6
Proteoglycan
Receptor Interacting Protein Serine Threonine Kinase 2
Tumor Necrosis Factor
Animals Cell
Animals Experiment
Animals Model
Animals Tissue
Arthritis
Cartilage Degeneration
Controlled Study
Enzyme Activity
Enzyme-linked Immunosorbent Assay
Enzyme Regulation
Histopathology
Immune Response
Mouse
Neutrophil
Nociception
Nonhuman
Priority Journal
Protein Expression
Protein Function
Reverse Transcription Polymerase Chain Reaction
Arthritis, Rheumatoid
Signal Transduction
Synovium
Animal
Arthritis, Experimental
Cattle
Cells, Cultured
Interleukin-17
Knee Joint
Mice
Mice, Inbred C57bl
Mice, Knockout
Nod1 Signaling Adaptor Protein
Nod2 Signaling Adaptor Protein
Receptor-interacting Protein Serine-threonine Kinases
Serum Albumin, Bovine
Signal Transduction
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/16128

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