HLA in Brazilian Ashkenazic Jews with chronic dermatophytosis caused by Trichophyton rubrum
The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically...
| Autor principal: | Sadahiro, Aya |
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| Outros Autores: | Feresin Moraes, José Roberto, Hue Moraes, Maria Elisa, Romero, Matilde, Lima Gouvea, Nancy Alves de, Gouvea, Celso José, Ogusku, Maurício Morishi, Campbell, Iphis Tenfuss, Zaitz, Clarisse |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Brazilian Journal of Microbiology
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/16396 |
| Resumo: |
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The frequency of HLA (Human Leucocyte Antigens) was analyzed in 25 non-consanguineous Brazilian Ashkenazic Jews, resident in the city of São Paulo, Brazil, suffering from chronic dermatophytosis caused by T. rubrum, and in 25 non-infected individuals belonging to the same ethnic group. Statistically significant values (p<0.05) were observed for HLA-B14 associated with resistance to chronic dermatophytosis and HLA-DQB1*06 (p=0.05) possibly related to susceptibility. These findings suggest that genes on the chromosome 6, in the region of the major histocompatibility complex, may influence the development of chronic dermatophytosis. |