Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists
Objective: Cutaneous leishmaniasis (CL) is more frequently reported in men than in women; this may be due to male-biased exposure to CL vectors, female-biased resistance against the disease or both. We sought to determine whether gender-specific exposure to vector habitats explains male-biased CL in...
| Autor principal: | Soares, Letícia |
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| Outros Autores: | Abad-Franch, Fernando, Ferraz, Gonçalo |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Tropical Medicine and International Health
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/17755 |
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oai:repositorio:1-17755 |
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oai:repositorio:1-17755 Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists Soares, Letícia Abad-Franch, Fernando Ferraz, Gonçalo Bayesian Analysis Comparative Study Disease Incidence Disease Vector Epidemiology Fly Gender Issue Leishmaniasis Questionnaire Survey Rural Area Adult Brasil Controlled Study Environmental Exposure Female Gender Bias Human Incidence Major Clinical Study Male Morbidity Prediction Prevalence Questionnaires Risk Factor Rural Area Self Report Skin Leishmaniasis Amazonia Analyse Bayésienne Análisis Bayesiano Bayesian Analysis Environmental Exposure Exposición Ambiental Exposition À L'environnement Leishmania (viannia) Guyanensis Phlebotominae Phlébotomie Adolescent Adult Animal Bayes Theorem Ecosystem Environmental Exposure Female Humans Incidence Leishmaniasis, Cutaneous Male Questionnaires Research Personnel Rivers Rural Population Sex Factors South America Young Adult Objective: Cutaneous leishmaniasis (CL) is more frequently reported in men than in women; this may be due to male-biased exposure to CL vectors, female-biased resistance against the disease or both. We sought to determine whether gender-specific exposure to vector habitats explains male-biased CL incidence in two human populations of central Amazonia. Methods: We compared the CL incidence in one population of field researchers (N = 166), with similar exposure for males and females, and one population of rural settlers (N = 646), where exposure is overall male-biased. We used a combination of questionnaires and clinical data to quantify CL cases, and modelled disease incidence in a Bayesian framework. Results: There was a moderately higher incidence of CL among men than among women in both populations, but male bias decreased as exposure time increased. Disease incidence was overall higher among field researchers, suggesting that they are an important but understudied CL risk group. Conclusion: Our comparison of two contrasting populations provided epidemiological evidence that CL incidence can be male-biased even when exposure is comparable in both sexes. © 2014 John Wiley & Sons Ltd. 2020-06-15T21:49:06Z 2020-06-15T21:49:06Z 2014 Artigo https://repositorio.inpa.gov.br/handle/1/17755 10.1111/tmi.12337 en Volume 19, Número 8, Pags. 988-995 Restrito Tropical Medicine and International Health |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Bayesian Analysis Comparative Study Disease Incidence Disease Vector Epidemiology Fly Gender Issue Leishmaniasis Questionnaire Survey Rural Area Adult Brasil Controlled Study Environmental Exposure Female Gender Bias Human Incidence Major Clinical Study Male Morbidity Prediction Prevalence Questionnaires Risk Factor Rural Area Self Report Skin Leishmaniasis Amazonia Analyse Bayésienne Análisis Bayesiano Bayesian Analysis Environmental Exposure Exposición Ambiental Exposition À L'environnement Leishmania (viannia) Guyanensis Phlebotominae Phlébotomie Adolescent Adult Animal Bayes Theorem Ecosystem Environmental Exposure Female Humans Incidence Leishmaniasis, Cutaneous Male Questionnaires Research Personnel Rivers Rural Population Sex Factors South America Young Adult |
| spellingShingle |
Bayesian Analysis Comparative Study Disease Incidence Disease Vector Epidemiology Fly Gender Issue Leishmaniasis Questionnaire Survey Rural Area Adult Brasil Controlled Study Environmental Exposure Female Gender Bias Human Incidence Major Clinical Study Male Morbidity Prediction Prevalence Questionnaires Risk Factor Rural Area Self Report Skin Leishmaniasis Amazonia Analyse Bayésienne Análisis Bayesiano Bayesian Analysis Environmental Exposure Exposición Ambiental Exposition À L'environnement Leishmania (viannia) Guyanensis Phlebotominae Phlébotomie Adolescent Adult Animal Bayes Theorem Ecosystem Environmental Exposure Female Humans Incidence Leishmaniasis, Cutaneous Male Questionnaires Research Personnel Rivers Rural Population Sex Factors South America Young Adult Soares, Letícia Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists |
| topic_facet |
Bayesian Analysis Comparative Study Disease Incidence Disease Vector Epidemiology Fly Gender Issue Leishmaniasis Questionnaire Survey Rural Area Adult Brasil Controlled Study Environmental Exposure Female Gender Bias Human Incidence Major Clinical Study Male Morbidity Prediction Prevalence Questionnaires Risk Factor Rural Area Self Report Skin Leishmaniasis Amazonia Analyse Bayésienne Análisis Bayesiano Bayesian Analysis Environmental Exposure Exposición Ambiental Exposition À L'environnement Leishmania (viannia) Guyanensis Phlebotominae Phlébotomie Adolescent Adult Animal Bayes Theorem Ecosystem Environmental Exposure Female Humans Incidence Leishmaniasis, Cutaneous Male Questionnaires Research Personnel Rivers Rural Population Sex Factors South America Young Adult |
| description |
Objective: Cutaneous leishmaniasis (CL) is more frequently reported in men than in women; this may be due to male-biased exposure to CL vectors, female-biased resistance against the disease or both. We sought to determine whether gender-specific exposure to vector habitats explains male-biased CL incidence in two human populations of central Amazonia. Methods: We compared the CL incidence in one population of field researchers (N = 166), with similar exposure for males and females, and one population of rural settlers (N = 646), where exposure is overall male-biased. We used a combination of questionnaires and clinical data to quantify CL cases, and modelled disease incidence in a Bayesian framework. Results: There was a moderately higher incidence of CL among men than among women in both populations, but male bias decreased as exposure time increased. Disease incidence was overall higher among field researchers, suggesting that they are an important but understudied CL risk group. Conclusion: Our comparison of two contrasting populations provided epidemiological evidence that CL incidence can be male-biased even when exposure is comparable in both sexes. © 2014 John Wiley & Sons Ltd. |
| format |
Artigo |
| author |
Soares, Letícia |
| author2 |
Abad-Franch, Fernando Ferraz, Gonçalo |
| author2Str |
Abad-Franch, Fernando Ferraz, Gonçalo |
| title |
Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists |
| title_short |
Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists |
| title_full |
Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists |
| title_fullStr |
Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists |
| title_full_unstemmed |
Epidemiology of cutaneous leishmaniasis in central Amazonia: A comparison of sex-biased incidence among rural settlers and field biologists |
| title_sort |
epidemiology of cutaneous leishmaniasis in central amazonia: a comparison of sex-biased incidence among rural settlers and field biologists |
| publisher |
Tropical Medicine and International Health |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/17755 |
| _version_ |
1787141780202848256 |
| score |
11.755432 |