Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish
Tandemly repeated sequences are a common feature of vertebrate mitochondrial DNA control regions. However, questions still remain about their mode of evolution and function. To better understand patterns of variation in length and to explore the existence of previously described domain, we have char...
| Autor principal: | Terêncio, Maria Leandra |
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| Outros Autores: | Schneider, Carlos Henrique, Gross, Maria Claudia, Feldberg, Eliana, Porto, Jorge Ivan Rebelo |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Mitochondrial DNA
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/17911 |
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oai:repositorio:1-17911 |
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oai:repositorio:1-17911 Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish Terêncio, Maria Leandra Schneider, Carlos Henrique Gross, Maria Claudia Feldberg, Eliana Porto, Jorge Ivan Rebelo Dna, Mitochondrial 5' Untranslated Region Dna Sequence Dna Structure Fish Genetic Variability Genome, Mitochondrial Nannostomus Eques Nannostomus Unifasciatus Nonhuman Priority Journal Promoter Region Tandemly Repeated Sequence Variable Number Of Tandem Repeat Animal Base Sequence Brasil Characiformes Dna, Mitochondrial Evolution, Molecular Minisatellite Repeats Mitochondria Molecular Sequence Data Phylogeny Sequence Alignment Sequence Analysis, Dna Tandem Repeat Sequences Nannostomus Nannostomus Unifasciatus Vertebrata Tandemly repeated sequences are a common feature of vertebrate mitochondrial DNA control regions. However, questions still remain about their mode of evolution and function. To better understand patterns of variation in length and to explore the existence of previously described domain, we have characterized the control region structure of the Amazonian ornamental fish Nannostomus eques and Nannostomus unifasciatus. The control region ranged from 1121 to 1142 bp in length and could be separated into three domains: the domain associated with the extended terminal associated sequences, the central conserved domain, and the conserved sequence blocks domain. In the first domain, we encountered a sequence repeated 10 times in tandem (variable number tandem repeat (VNTR)) that could adopt an "inverted repetitions" type structural conformation. The results suggest that the VNTR pattern encountered in both N. eques and N. unifasciatus is consistent with the prerequisites of the illegitimate elongation model in which the unequal pairing of the chains near the 5′-end of the control region favors the formation of repetitions. © 2021 Informa UK, Ltd. 2020-06-15T21:50:04Z 2020-06-15T21:50:04Z 2013 Artigo https://repositorio.inpa.gov.br/handle/1/17911 10.3109/19401736.2012.717934 en Volume 24, Número 1, Pags. 74-82 Restrito Mitochondrial DNA |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Dna, Mitochondrial 5' Untranslated Region Dna Sequence Dna Structure Fish Genetic Variability Genome, Mitochondrial Nannostomus Eques Nannostomus Unifasciatus Nonhuman Priority Journal Promoter Region Tandemly Repeated Sequence Variable Number Of Tandem Repeat Animal Base Sequence Brasil Characiformes Dna, Mitochondrial Evolution, Molecular Minisatellite Repeats Mitochondria Molecular Sequence Data Phylogeny Sequence Alignment Sequence Analysis, Dna Tandem Repeat Sequences Nannostomus Nannostomus Unifasciatus Vertebrata |
| spellingShingle |
Dna, Mitochondrial 5' Untranslated Region Dna Sequence Dna Structure Fish Genetic Variability Genome, Mitochondrial Nannostomus Eques Nannostomus Unifasciatus Nonhuman Priority Journal Promoter Region Tandemly Repeated Sequence Variable Number Of Tandem Repeat Animal Base Sequence Brasil Characiformes Dna, Mitochondrial Evolution, Molecular Minisatellite Repeats Mitochondria Molecular Sequence Data Phylogeny Sequence Alignment Sequence Analysis, Dna Tandem Repeat Sequences Nannostomus Nannostomus Unifasciatus Vertebrata Terêncio, Maria Leandra Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish |
| topic_facet |
Dna, Mitochondrial 5' Untranslated Region Dna Sequence Dna Structure Fish Genetic Variability Genome, Mitochondrial Nannostomus Eques Nannostomus Unifasciatus Nonhuman Priority Journal Promoter Region Tandemly Repeated Sequence Variable Number Of Tandem Repeat Animal Base Sequence Brasil Characiformes Dna, Mitochondrial Evolution, Molecular Minisatellite Repeats Mitochondria Molecular Sequence Data Phylogeny Sequence Alignment Sequence Analysis, Dna Tandem Repeat Sequences Nannostomus Nannostomus Unifasciatus Vertebrata |
| description |
Tandemly repeated sequences are a common feature of vertebrate mitochondrial DNA control regions. However, questions still remain about their mode of evolution and function. To better understand patterns of variation in length and to explore the existence of previously described domain, we have characterized the control region structure of the Amazonian ornamental fish Nannostomus eques and Nannostomus unifasciatus. The control region ranged from 1121 to 1142 bp in length and could be separated into three domains: the domain associated with the extended terminal associated sequences, the central conserved domain, and the conserved sequence blocks domain. In the first domain, we encountered a sequence repeated 10 times in tandem (variable number tandem repeat (VNTR)) that could adopt an "inverted repetitions" type structural conformation. The results suggest that the VNTR pattern encountered in both N. eques and N. unifasciatus is consistent with the prerequisites of the illegitimate elongation model in which the unequal pairing of the chains near the 5′-end of the control region favors the formation of repetitions. © 2021 Informa UK, Ltd. |
| format |
Artigo |
| author |
Terêncio, Maria Leandra |
| author2 |
Schneider, Carlos Henrique Gross, Maria Claudia Feldberg, Eliana Porto, Jorge Ivan Rebelo |
| author2Str |
Schneider, Carlos Henrique Gross, Maria Claudia Feldberg, Eliana Porto, Jorge Ivan Rebelo |
| title |
Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish |
| title_short |
Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish |
| title_full |
Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish |
| title_fullStr |
Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish |
| title_full_unstemmed |
Structure and organization of the mitochondrial DNA control region with tandemly repeated sequence in the Amazon ornamental fish |
| title_sort |
structure and organization of the mitochondrial dna control region with tandemly repeated sequence in the amazon ornamental fish |
| publisher |
Mitochondrial DNA |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/17911 |
| _version_ |
1787141933169115136 |
| score |
11.653393 |