Artigo

In vivo and in vitro antimalarial activity of 4-nerolidylcatechol

4-Nerolidylcatechol (4-NC) isolated from Piper peltatum L. (Piperaceae) was evaluated for in vitro antiplasmodial activity against Plasmodium falciparum (cultures of both standard CQR (K1) and CQS (3D7) strains and two Amazonian field isolates) and for in vivo antimalarial activity using the Plasmod...

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Autor principal: Silva, Luiz Francisco Rocha e
Outros Autores: Pinto, Ana Cristina da Silva, Pohlit, Adrian Martin, Quignard, Etienne Louis Jacques, Vieira, Pedro Paulo Ribeiro, Tadei, Wanderli Pedro, Chaves, Francisco Célio Maia, Samonek, Jean Francisco, Lima, Carlos Alberto Jatoba, Costa, Mônica Regina Farias, Alecrim, Maria das Graças Costa, Andrade Neto, Valter Ferreira de
Grau: Artigo
Idioma: English
Publicado em: Phytotherapy Research 2020
Assuntos:
4 Nerolidylcatechol
Antimalarial Agent
Catechol Derivative
Chloroquine
Unclassified Drug
Animals Cell
Animals Experiment
Animals Model
Antimalarial Activity
Blood Sampling
Concentration (parameters)
Controlled Study
Drug Determination
Drug Dose Comparison
Drug Inhibition
Drug Metabolism
Drug Structure
Female
Growth Inhibition
Human
Human Cell
In Vitro Study
In Vivo Study
Malaria
Microbial Growth
Mouse
Nonhuman
Piper Peltatum
Piperaceae
Plasmodium Berghei
Plasmodium Falciparum
Treatment Response
Animal
Antimalarials
Brasil
Catechols
Disease Models, Animals
Female
Malaria
Malaria, Falciparum
Mice
Piper
Plasmodium Berghei
Plasmodium Falciparum
Murinae
Mus
Piper Peltatum
Piperaceae
Plasmodium Berghei
Plasmodium Falciparum
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/18169

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