Artigo

The biological activity of extracts, hydrolates, and volatile oils of Aniba duckei Kostermans and the quantification of linalol in the leaf hydrolate

The objective of this study was to evaluate the bioactivity of extracts and by-products of volatile oil extraction from rosewood, as well as to quantify linalool levels in hydrolates. Branch and trunkwood methanol extracts presented significant lethality to Artemia franciscana larvae (LC 50 58 ± 33...

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Autor principal: Souza, K. S.
Outros Autores: Chaar, Jamal da Silva, Oliveira, Kelson Mota Teixeira de, Gomes, E. O., Portela, Cíntia Nicácio, Pohlit, Adrian Martin, Quignard, Etienne Louis Jacques, Nunomura, Sergio Massayoshi, Tadei, Wanderli Pedro, Mouchrek Filho, Victor Elias, Silva, D. D., Galhiane, Mário Sérgio, Chierice, Gilberto Orivaldo
Grau: Artigo
Idioma: pt_BR
Publicado em: Revista Brasileira de Plantas Medicinais 2020
Assuntos:
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/18663
Resumo:
The objective of this study was to evaluate the bioactivity of extracts and by-products of volatile oil extraction from rosewood, as well as to quantify linalool levels in hydrolates. Branch and trunkwood methanol extracts presented significant lethality to Artemia franciscana larvae (LC 50 58 ± 33 and 71 ± 31 mg mL -1, respectively). Hydrolates (diluted to 25%) and volatile oil (2 mg mL -1) caused 100% mortality. These results show that A. duckei is a potential source of cytotoxic substances. The volatile oil obtained from branchwood presented larvicidal activity in vitro towards Aedes aegypti (hemorrhagic dengue fever vector, LC 50 2,2 g L -1). Quantitative GC analysis performed on the hydrolate obtained from leaf extraction revealed a linalool concentration of 0.09% v/v (6 mM), which could be responsible for the observed bioactivity.