A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout
The present study examined the interactions between elevated dietary calcium (as ionic Ca2+ in the form of CaCl2·2H 2O) and acute waterborne Cd exposure (50μg/l as CdNO3 for 3h) on whole body uptake and internal distribution of newly accumulated Cd, Ca2+, and Na+ in juvenile rainbow trout (Oncorhync...
| Autor principal: | Baldisserotto, Bernardo |
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| Outros Autores: | Kamunde, Collins N., Matsuo, Aline Y.O., Wood, Chris M. |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Aquatic Toxicology
2020
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| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/18929 |
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oai:repositorio:1-18929 |
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oai:repositorio:1-18929 A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout Baldisserotto, Bernardo Kamunde, Collins N. Matsuo, Aline Y.O. Wood, Chris M. Cadmium Bioaccumulation Cadmium Calcium Diet Fish Animals Experiment Calcium Intake Controlled Study Gastrointestinal Absorption Internalization Nonhuman Priority Journal Protection Rainbow Trout Invertebrata Oncorhynchus Oncorhynchus Mykiss Oncorhynchus Mykiss Salmonidae The present study examined the interactions between elevated dietary calcium (as ionic Ca2+ in the form of CaCl2·2H 2O) and acute waterborne Cd exposure (50μg/l as CdNO3 for 3h) on whole body uptake and internal distribution of newly accumulated Cd, Ca2+, and Na+ in juvenile rainbow trout (Oncorhynchus mykiss). Fish were fed with three diets 20 (control), 30 and 60mg Ca 2+/g food: for 7 days before fluxes were measured with radiotracers over a 3h period. The two elevated Ca2+ diets reduced the whole body uptake of both Ca2+ and Cd by >50% and similarly reduced the internalization of both newly accumulated metals in most tissues, effects which reflect the shared branchial uptake route for Ca2+ and Cd. As the Ca2+ concentrations of the fluid phases of the stomach and intestinal contents were greatly elevated by the experimental diets, increased gastrointestinal Ca2+ uptake likely caused the down-regulation of the branchial Ca2+ (and Cd) uptake pathway. Waterborne Na + uptake and internal distribution were not affected. While plasma Ca2+ surged after the first two feedings of the 60mg Ca 2+/g diet, internal homeostasis was quickly restored. Total Ca 2+, Na+, and Cl- levels in tissues were not affected by diets. While dietary Ca2+ protected against waterborne Cd uptake, it did not protect against the relative inhibition of waterborne Ca2+ uptake caused by waterborne Cd. Acute exposure to 50μg/l Cd reduced the uptake and internalization of newly accumulated Ca2+ (but not Na+) by 70% or more, regardless of diet. Since elevated dietary Ca2+ reduces waterborne Cd uptake, fish eating a Ca 2+-rich invertebrate diet may be more protected against waterborne Cd toxicity in a field situation. © 2004 Elsevier B.V. All rights reserved. 2020-06-15T22:03:58Z 2020-06-15T22:03:58Z 2004 Artigo https://repositorio.inpa.gov.br/handle/1/18929 10.1016/j.aquatox.2003.12.004 en Volume 67, Número 1, Pags. 57-73 Restrito Aquatic Toxicology |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Cadmium Bioaccumulation Cadmium Calcium Diet Fish Animals Experiment Calcium Intake Controlled Study Gastrointestinal Absorption Internalization Nonhuman Priority Journal Protection Rainbow Trout Invertebrata Oncorhynchus Oncorhynchus Mykiss Oncorhynchus Mykiss Salmonidae |
| spellingShingle |
Cadmium Bioaccumulation Cadmium Calcium Diet Fish Animals Experiment Calcium Intake Controlled Study Gastrointestinal Absorption Internalization Nonhuman Priority Journal Protection Rainbow Trout Invertebrata Oncorhynchus Oncorhynchus Mykiss Oncorhynchus Mykiss Salmonidae Baldisserotto, Bernardo A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| topic_facet |
Cadmium Bioaccumulation Cadmium Calcium Diet Fish Animals Experiment Calcium Intake Controlled Study Gastrointestinal Absorption Internalization Nonhuman Priority Journal Protection Rainbow Trout Invertebrata Oncorhynchus Oncorhynchus Mykiss Oncorhynchus Mykiss Salmonidae |
| description |
The present study examined the interactions between elevated dietary calcium (as ionic Ca2+ in the form of CaCl2·2H 2O) and acute waterborne Cd exposure (50μg/l as CdNO3 for 3h) on whole body uptake and internal distribution of newly accumulated Cd, Ca2+, and Na+ in juvenile rainbow trout (Oncorhynchus mykiss). Fish were fed with three diets 20 (control), 30 and 60mg Ca 2+/g food: for 7 days before fluxes were measured with radiotracers over a 3h period. The two elevated Ca2+ diets reduced the whole body uptake of both Ca2+ and Cd by >50% and similarly reduced the internalization of both newly accumulated metals in most tissues, effects which reflect the shared branchial uptake route for Ca2+ and Cd. As the Ca2+ concentrations of the fluid phases of the stomach and intestinal contents were greatly elevated by the experimental diets, increased gastrointestinal Ca2+ uptake likely caused the down-regulation of the branchial Ca2+ (and Cd) uptake pathway. Waterborne Na + uptake and internal distribution were not affected. While plasma Ca2+ surged after the first two feedings of the 60mg Ca 2+/g diet, internal homeostasis was quickly restored. Total Ca 2+, Na+, and Cl- levels in tissues were not affected by diets. While dietary Ca2+ protected against waterborne Cd uptake, it did not protect against the relative inhibition of waterborne Ca2+ uptake caused by waterborne Cd. Acute exposure to 50μg/l Cd reduced the uptake and internalization of newly accumulated Ca2+ (but not Na+) by 70% or more, regardless of diet. Since elevated dietary Ca2+ reduces waterborne Cd uptake, fish eating a Ca 2+-rich invertebrate diet may be more protected against waterborne Cd toxicity in a field situation. © 2004 Elsevier B.V. All rights reserved. |
| format |
Artigo |
| author |
Baldisserotto, Bernardo |
| author2 |
Kamunde, Collins N. Matsuo, Aline Y.O. Wood, Chris M. |
| author2Str |
Kamunde, Collins N. Matsuo, Aline Y.O. Wood, Chris M. |
| title |
A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| title_short |
A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| title_full |
A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| title_fullStr |
A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| title_full_unstemmed |
A protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| title_sort |
protective effect of dietary calcium against acute waterborne cadmium uptake in rainbow trout |
| publisher |
Aquatic Toxicology |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/18929 |
| _version_ |
1787142611502366720 |
| score |
11.653393 |