Molecular evolution of the period gene in sandflies
The molecular evolution of the clock gene period was studied in Phlebotomine sandflies (Diptera: Psychodidae). Comparison of the synonymous and nonsynonymous substitution rates between sandflies and Drosophila revealed a significantly higher evolutionary rate in the latter in three of the four regio...
| Autor principal: | Mazzoni, Camila Junqueira |
|---|---|
| Outros Autores: | Gomes, C. A., Souza, Nataly Araújo de, Queiroz, R. G., Justiniano, Sílvia Cássia Brandão, Ward, Richard Douglas, Kyriacou, Charalambos Panayiotis, Peixoto, Alexandre Afrânio |
| Grau: | Artigo |
| Idioma: | English |
| Publicado em: |
Journal of Molecular Evolution
2020
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| Assuntos: | |
| Acesso em linha: |
https://repositorio.inpa.gov.br/handle/1/19038 |
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oai:repositorio:1-19038 |
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dspace |
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oai:repositorio:1-19038 Molecular evolution of the period gene in sandflies Mazzoni, Camila Junqueira Gomes, C. A. Souza, Nataly Araújo de Queiroz, R. G. Justiniano, Sílvia Cássia Brandão Ward, Richard Douglas Kyriacou, Charalambos Panayiotis Peixoto, Alexandre Afrânio Glycine Threonine Controlled Study Dna Flanking Region Drosophila Gene Gene Location Genus Molecular Clock Evolution, Molecular Morphology Neotropics Nonhuman Nucleic Acid Base Substitution Nucleotide Repeat Nucleotide Sequence Parsimony Analysis Period Gene Phlebotomus Phylogeny Species Comparison Amino Acid Sequence Animal Base Sequence Biological Clocks Dna Evolution, Molecular Genes, Insect Molecular Sequence Data Nuclear Proteins Phylogeny Psychodidae Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Arachnida Diptera Hexapoda Lutzomyia Migonei Migonei Group Nyssomyia Phlebotominae Psychodidae The molecular evolution of the clock gene period was studied in Phlebotomine sandflies (Diptera: Psychodidae). Comparison of the synonymous and nonsynonymous substitution rates between sandflies and Drosophila revealed a significantly higher evolutionary rate in the latter in three of the four regions analyzed. The differences in rate were higher in the sequences flanking the Thr-Gly repetitive domain, a region that has expanded in Drosophila but remained stable and short in sandflies, a result consistent with the coevolutionary scenario proposed for this region of the gene. An initial phylogenetic analysis including eight neotropical sandfly species and one from the Old World was also carried out. The results showed that only the subgenus Nyssomyia is well supported by distance (neighbor-joining) and maximum parsimony analysis. The grouping of the other species from the subgenus Lutzomyia and Migonei group shows very low boot-strap values and is not entirely consistent with classical morphological systematics of the genus Lutzomyia. 2020-06-15T22:04:50Z 2020-06-15T22:04:50Z 2002 Artigo https://repositorio.inpa.gov.br/handle/1/19038 10.1007/s00239-002-2351-z en Volume 55, Número 5, Pags. 553-562 Restrito Journal of Molecular Evolution |
| institution |
Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional |
| collection |
INPA-RI |
| language |
English |
| topic |
Glycine Threonine Controlled Study Dna Flanking Region Drosophila Gene Gene Location Genus Molecular Clock Evolution, Molecular Morphology Neotropics Nonhuman Nucleic Acid Base Substitution Nucleotide Repeat Nucleotide Sequence Parsimony Analysis Period Gene Phlebotomus Phylogeny Species Comparison Amino Acid Sequence Animal Base Sequence Biological Clocks Dna Evolution, Molecular Genes, Insect Molecular Sequence Data Nuclear Proteins Phylogeny Psychodidae Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Arachnida Diptera Hexapoda Lutzomyia Migonei Migonei Group Nyssomyia Phlebotominae Psychodidae |
| spellingShingle |
Glycine Threonine Controlled Study Dna Flanking Region Drosophila Gene Gene Location Genus Molecular Clock Evolution, Molecular Morphology Neotropics Nonhuman Nucleic Acid Base Substitution Nucleotide Repeat Nucleotide Sequence Parsimony Analysis Period Gene Phlebotomus Phylogeny Species Comparison Amino Acid Sequence Animal Base Sequence Biological Clocks Dna Evolution, Molecular Genes, Insect Molecular Sequence Data Nuclear Proteins Phylogeny Psychodidae Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Arachnida Diptera Hexapoda Lutzomyia Migonei Migonei Group Nyssomyia Phlebotominae Psychodidae Mazzoni, Camila Junqueira Molecular evolution of the period gene in sandflies |
| topic_facet |
Glycine Threonine Controlled Study Dna Flanking Region Drosophila Gene Gene Location Genus Molecular Clock Evolution, Molecular Morphology Neotropics Nonhuman Nucleic Acid Base Substitution Nucleotide Repeat Nucleotide Sequence Parsimony Analysis Period Gene Phlebotomus Phylogeny Species Comparison Amino Acid Sequence Animal Base Sequence Biological Clocks Dna Evolution, Molecular Genes, Insect Molecular Sequence Data Nuclear Proteins Phylogeny Psychodidae Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid Arachnida Diptera Hexapoda Lutzomyia Migonei Migonei Group Nyssomyia Phlebotominae Psychodidae |
| description |
The molecular evolution of the clock gene period was studied in Phlebotomine sandflies (Diptera: Psychodidae). Comparison of the synonymous and nonsynonymous substitution rates between sandflies and Drosophila revealed a significantly higher evolutionary rate in the latter in three of the four regions analyzed. The differences in rate were higher in the sequences flanking the Thr-Gly repetitive domain, a region that has expanded in Drosophila but remained stable and short in sandflies, a result consistent with the coevolutionary scenario proposed for this region of the gene. An initial phylogenetic analysis including eight neotropical sandfly species and one from the Old World was also carried out. The results showed that only the subgenus Nyssomyia is well supported by distance (neighbor-joining) and maximum parsimony analysis. The grouping of the other species from the subgenus Lutzomyia and Migonei group shows very low boot-strap values and is not entirely consistent with classical morphological systematics of the genus Lutzomyia. |
| format |
Artigo |
| author |
Mazzoni, Camila Junqueira |
| author2 |
Gomes, C. A. Souza, Nataly Araújo de Queiroz, R. G. Justiniano, Sílvia Cássia Brandão Ward, Richard Douglas Kyriacou, Charalambos Panayiotis Peixoto, Alexandre Afrânio |
| author2Str |
Gomes, C. A. Souza, Nataly Araújo de Queiroz, R. G. Justiniano, Sílvia Cássia Brandão Ward, Richard Douglas Kyriacou, Charalambos Panayiotis Peixoto, Alexandre Afrânio |
| title |
Molecular evolution of the period gene in sandflies |
| title_short |
Molecular evolution of the period gene in sandflies |
| title_full |
Molecular evolution of the period gene in sandflies |
| title_fullStr |
Molecular evolution of the period gene in sandflies |
| title_full_unstemmed |
Molecular evolution of the period gene in sandflies |
| title_sort |
molecular evolution of the period gene in sandflies |
| publisher |
Journal of Molecular Evolution |
| publishDate |
2020 |
| url |
https://repositorio.inpa.gov.br/handle/1/19038 |
| _version_ |
1787144558488846336 |
| score |
11.755432 |