Artigo

Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil

A skin test survey with paracoccidioidin and histoplasmin was conducted on 495 residents of Coari in the Brazilian state of Amazonas. Positive dermal reactions to paracoccidioidin and histoplasmin were seen, respectively, in 13.9% and 50.1% of the study subjects. Specific reaction to paracoccidioidi...

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Autor principal: Mok, Waiyin
Outros Autores: Fava-Netto, Celeste
Grau: Artigo
Idioma: English
Publicado em: American Journal of Tropical Medicine and Hygiene 2020
Assuntos:
Acesso em linha: https://repositorio.inpa.gov.br/handle/1/19760
id oai:repositorio:1-19760
recordtype dspace
spelling oai:repositorio:1-19760 Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil Mok, Waiyin Fava-Netto, Celeste Histoplasmin Para Coccidiodin Unclassified Drug Blastomycosis Brasil Cross Reaction Diagnosis Epidemiology Fungus Geographic Distribution Histoplasmosis Human Cell Methodology Normal Human Reticuloendothelial System Short Survey Skin Test A skin test survey with paracoccidioidin and histoplasmin was conducted on 495 residents of Coari in the Brazilian state of Amazonas. Positive dermal reactions to paracoccidioidin and histoplasmin were seen, respectively, in 13.9% and 50.1% of the study subjects. Specific reaction to paracoccidioidin was observed in 1.6% of the individuals, and to histoplasmin in 37.8%. Cross-reactivity between the two antigens in persons who reacted positively to both skin tests was not totally reciprocal. There were no significant differences in dermal reactivity to either of the two antigens in either sex, or among different occupational groups. No precipitating antibody to paracoccidioidin or histoplasmin was detected in the sera of the skin test-positive individuals by the immunodiffusion test. Skin test positivity in the general population of Coari reaffirmed the concept of benign, self-limited infection in paracoccidioidomycosis and histoplasmosis. It also identified the equatorial forests of the Upper Amazon Basin as endemic zones of these two mycoses. 2020-06-15T22:12:36Z 2020-06-15T22:12:36Z 1978 Artigo https://repositorio.inpa.gov.br/handle/1/19760 10.4269/ajtmh.1978.27.808 en Volume 27, Número 4, Pags. 808-814 Restrito American Journal of Tropical Medicine and Hygiene
institution Instituto Nacional de Pesquisas da Amazônia - Repositório Institucional
collection INPA-RI
language English
topic Histoplasmin
Para Coccidiodin
Unclassified Drug
Blastomycosis
Brasil
Cross Reaction
Diagnosis
Epidemiology
Fungus
Geographic Distribution
Histoplasmosis
Human Cell
Methodology
Normal Human
Reticuloendothelial System
Short Survey
Skin Test
spellingShingle Histoplasmin
Para Coccidiodin
Unclassified Drug
Blastomycosis
Brasil
Cross Reaction
Diagnosis
Epidemiology
Fungus
Geographic Distribution
Histoplasmosis
Human Cell
Methodology
Normal Human
Reticuloendothelial System
Short Survey
Skin Test
Mok, Waiyin
Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil
topic_facet Histoplasmin
Para Coccidiodin
Unclassified Drug
Blastomycosis
Brasil
Cross Reaction
Diagnosis
Epidemiology
Fungus
Geographic Distribution
Histoplasmosis
Human Cell
Methodology
Normal Human
Reticuloendothelial System
Short Survey
Skin Test
description A skin test survey with paracoccidioidin and histoplasmin was conducted on 495 residents of Coari in the Brazilian state of Amazonas. Positive dermal reactions to paracoccidioidin and histoplasmin were seen, respectively, in 13.9% and 50.1% of the study subjects. Specific reaction to paracoccidioidin was observed in 1.6% of the individuals, and to histoplasmin in 37.8%. Cross-reactivity between the two antigens in persons who reacted positively to both skin tests was not totally reciprocal. There were no significant differences in dermal reactivity to either of the two antigens in either sex, or among different occupational groups. No precipitating antibody to paracoccidioidin or histoplasmin was detected in the sera of the skin test-positive individuals by the immunodiffusion test. Skin test positivity in the general population of Coari reaffirmed the concept of benign, self-limited infection in paracoccidioidomycosis and histoplasmosis. It also identified the equatorial forests of the Upper Amazon Basin as endemic zones of these two mycoses.
format Artigo
author Mok, Waiyin
author2 Fava-Netto, Celeste
author2Str Fava-Netto, Celeste
title Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil
title_short Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil
title_full Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil
title_fullStr Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil
title_full_unstemmed Paracoccidioidin and histoplasmin sensitivity in Coari (state of Amazonas), Brazil
title_sort paracoccidioidin and histoplasmin sensitivity in coari (state of amazonas), brazil
publisher American Journal of Tropical Medicine and Hygiene
publishDate 2020
url https://repositorio.inpa.gov.br/handle/1/19760
_version_ 1787142287042543616
score 11.755432