Ultrasound (US) is one of the therapeutic physical therapies commonly used in physical
therapy as eletrotermoterapêutico feature to control the inflammatory process and acceleration
of tissue healing process. Among the US Therapeutic implementing rules have the
phonophoresis method. A long time copaíba OR is recognized and used by traditional
communities as a natural resource in the treatment of inflammatory disorders. This study aims
to study the associated application of OR copaíba gel with phonophoresis method, since there
are few research carried this theme, and nonexistent in relation to the species Copaifera
duckei Dwyer. Thus, this study aimed to evaluate the therapeutic action of a herbal gel OR
C.duckei administered through the phonophoresis method on the inflammatory phase of the
muscle repair process. For this purpose an experimental study with the production of a gel
C.duckei 10% and then its administration by phonophoresis on the gastrocnemius muscle
subjected to trauma-induced free fall type mechanism was conducted in order to examine its
effect on the phase inflammatory muscle recovery process, considering the variables
histological analysis, fibrosis, necrosis, edema, and inflammatory infiltrate cells with
centralized cores. Further analysis on acute toxicity and repeated dose applications were also
performed by using the OECD 404 and OECD 410, protocols and other analysis for pH and
the transmissibility of gel in addition to the potential opening of the stratum corneum of the
skin as well were realized. The data for this analysis were tabulated in Excell spreadsheet
software (Microsoft ® - USA), and later received statistical treatment by BioEstat 5.3
software. For this experimental study was admitted to the 0.05 significance level (α = 0.05 or
5%), to a sampling error of 5% for all analyzes. We conclude that all therapies used showed
significant results in the muscle repair process when compared to the control group.
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