The introduction of antiretroviral therapy resulted in a reduction in opportunistic infections associated with HIV, consequently reducing the incidence of most neurological diseases in HIV-positive patients. However, neurocognitive changes associated with HIV (HAND) remain at a significant prevalence, even in individuals using antiretroviral drugs. The present study aimed to evaluate possible cognitive deficits in HIV-positive patients and characterize the clinical profile of neurocognitive manifestations in the Northern region of Brazil. 30 HIVpositive patients were evaluated, treated at the Health Care Center for Acquired Infectious Diseases (CASA DIA), in Belém do Pará. It was possible to verify a decline in neurological functions, which affect the functional capacity of these PLHIV, with emphasis on the cognitive domain of memory and attention, where it was possible to identify through IADLs, IHDS and CANTAB.
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