Câncer de vesícula biliar: experiência de 10 anos em um hospital de referência da Amazônia
Objective: To evaluate the epidemiological aspects of surgical patients with gallbladder cancer (GC) enrolled in a University Hospital in Belém (State of Pará – PA), in the period 1999-2009. Methods: observational, retrospective, descriptive and analytical study of secondary sources of patients wit...
| Autor principal: | ISHAK, Geraldo |
|---|---|
| Outros Autores: | RIBEIRO, Felipe Soares, COSTA, Daniel Souza da, BAHIA, Leandro Augusto Costa, DIAS, Everton Mesquita, ASSUMPÇÃO, Paulo Pimentel de |
| Grau: | Artigo |
| Idioma: | por eng |
| Publicado em: |
2013
|
| Assuntos: | |
| Acesso em linha: |
http://repositorio.ufpa.br/jspui/handle/2011/3887 |
| Resumo: |
|---|
|
Objective: To evaluate the epidemiological aspects of surgical patients with gallbladder cancer (GC) enrolled in a University Hospital in Belém (State of Pará – PA), in the period 1999-2009. Methods: observational, retrospective, descriptive and analytical
study of secondary sources of patients with GC in the period 1999-2009. We analyzed 75 medical records, with 34 patients studied. The information collected was used for the TNM tumor staging of GC and to characterize the clinical and surgical population. Results: 79% were female, mean age 66.2 ± 11 years and duration of symptoms was 10.8 ± 17.2 months, with no statistical relationship with the stage of disease. Pain in right upper quadrant, nausea and jaundice prevailed as signs / symptoms. Gallstones were present in 91% of cases and were positive in 100% of patients with stage I / II. The sensitivity of ultrasound to preoperatively suggest GC was 14.28%. The simplest operation performed was cholecystectomy, with the predominant intraoperative finding being hepatic invasion. Adenocarcinoma was the predominant histologic type, especially for stages III and
IV. Conclusion: The present study showed high incidence of gallstone disease. Advanced stage adenocarcinoma was the most prevalent. This resulted in a low rate of operations with curative intent, in 30% of the patients, and a mortality rate of 21%. The appreciation of symptoms and early investigation by imaging could facilitate treatment in early stages of GC, providing a better prognosis for patients. |