Hepatitis B and C virus infection among Brazilian Amazon riparians
INTRODUCTION: Viral hepatitis is a major public health concern in Brazil. There are few past studies on this issue, especially among riparian communities. This study aims at determining the seroprevalence of viral hepatitis B and C in the riparian community of Pacuí Island, within the Cametá municip...
| Autor principal: | OLIVEIRA, Claudia Suellen Ferro de |
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| Outros Autores: | SILVA, Adenielson Vilar e, SANTOS, Kemper Nunes dos, FECURY, Amanda Alves, ALMEIDA, Marcella Kelly Costa de, FERNANDES, Adriana Prado, COSTA, Carlos Araújo da, FREITAS, Andrei Silva, CORVELO, Tereza Cristina de Oliveira, MARTINS, Luisa Caricio |
| Grau: | Artigo |
| Idioma: | eng |
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2014
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http://repositorio.ufpa.br/jspui/handle/2011/6162 |
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ir-2011-6162 |
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ir-2011-61622019-05-23T11:11:47Z Hepatitis B and C virus infection among Brazilian Amazon riparians Infecção pelo virus da hepatite B e C em ribeirinhos da Amazônia brasileira OLIVEIRA, Claudia Suellen Ferro de SILVA, Adenielson Vilar e SANTOS, Kemper Nunes dos FECURY, Amanda Alves ALMEIDA, Marcella Kelly Costa de FERNANDES, Adriana Prado COSTA, Carlos Araújo da FREITAS, Andrei Silva CORVELO, Tereza Cristina de Oliveira MARTINS, Luisa Caricio Hepatite Hepatite B Hepatite C Hepatite por vírus Vírus da hepatite B Vírus da hepatite C Soroprevalência Ribeirinhos Cametá - PA Pará - Estado Amazônia brasileira INTRODUCTION: Viral hepatitis is a major public health concern in Brazil. There are few past studies on this issue, especially among riparian communities. This study aims at determining the seroprevalence of viral hepatitis B and C in the riparian community of Pacuí Island, within the Cametá municipality of Pará State, Brazil. Moreover, this study aims to investigate the principal risk factors that this community is exposed to. METHODS: The current study has accessed blood samples from 181 volunteers who have answered an epidemiological questionnaire. Analyses on serological markers have been tested with commercial ELISA kits for detecting HBsAg, total anti-HBc, anti-HBs, and anti-HCV. Within seroreactive patients for HCV, RT-PCR and line probe assay have been performed to identify the viral genotype. RESULTS: In the serological marker analysis for hepatitis B, no reactivity for HBsAg, rate of 1.1% for total anti-HBc, and rate of 19.3% for anti-HBs have been observed. On hepatitis C, 8.8% seroprevalence has been found, in which 62.5% have gotten viral RNA. Among the risk factors studied, the following have been highlighted: non-use of condoms, sharing of cutting instruments, use of illicit drugs, and reports of family disease with HBV or HCV. CONCLUSIONS: The vaccination coverage against HBV is low, and the high prevalence of HCV within this community has been observed. INTRODUÇÃO: As hepatites virais constituem um importante problema de saúde pública no mundo. No Brasil existem poucos estudos sobre esta questão, especialmente entre as comunidades ribeirinhas. O objetivo deste estudo foi determinar a soroprevalência das hepatites B e C virais na comunidade ribeirinha da Ilha do Pacuí, no Estado do Pará, Brasil, e investigar os principais fatores de risco principal a que está comunidade está exposta. MÉTODOS: O presente estudo avaliou amostras de sangue de 181 voluntários que responderam a um questionário epidemiológico. Análises de marcadores sorológicos foram testados com kits comerciais de ELISA para detecção de HBsAg, anti-HBc total, anti-HBs e anti-VHC. Nos pacientes reagentes para VHC, RT-PCR e um line probe assay foi realizado para identificar o genótipo viral. RESULTADOS: Na análise dos marcadores sorológicos para hepatite B, observou-se taxas de 1,1% para anti-HBc total e 19,3% para anti-HBs, o marcador sorológico HBsAg não foi encontrado nesta população. Para a hepatite C foi encontrada um soroprevalência de 8,8%, destes 62,5% tinham RNA viral. Entre os fatores de risco estudados se destacaram: a não-utilização de preservativos, o compartilhamento de instrumentos cortantes, uso de drogas ilícitas e relatos de doença na família com VHB ou VHC. CONCLUSÕES: Observamos que a cobertura de vacinação contra o VHB é baixa e uma alta prevalência da hepatite C nesta comunidade. 2014-12-15T16:30:17Z 2014-12-15T16:30:17Z 2011-10 Artigo de Periódico OLIVEIRA, Claudia Suellen Ferro de et al. Hepatitis B and C virus infection among Brazilian Amazon riparians. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 44, n. 5, p. 546-550, set./out. 2011. Disponível em: <http://www.scielo.br/pdf/rsbmt/v44n5/03.pdf>. Acesso em: 12 dez. 2014. <http://dx.doi.org/10.1590/S0037-86822011000500003>. 0037-8682 http://repositorio.ufpa.br/jspui/handle/2011/6162 eng Acesso Aberto application/pdf |
| institution |
Repositório Institucional - Universidade Federal do Pará |
| collection |
RI-UFPA |
| language |
eng |
| topic |
Hepatite Hepatite B Hepatite C Hepatite por vírus Vírus da hepatite B Vírus da hepatite C Soroprevalência Ribeirinhos Cametá - PA Pará - Estado Amazônia brasileira |
| spellingShingle |
Hepatite Hepatite B Hepatite C Hepatite por vírus Vírus da hepatite B Vírus da hepatite C Soroprevalência Ribeirinhos Cametá - PA Pará - Estado Amazônia brasileira OLIVEIRA, Claudia Suellen Ferro de Hepatitis B and C virus infection among Brazilian Amazon riparians |
| topic_facet |
Hepatite Hepatite B Hepatite C Hepatite por vírus Vírus da hepatite B Vírus da hepatite C Soroprevalência Ribeirinhos Cametá - PA Pará - Estado Amazônia brasileira |
| description |
INTRODUCTION: Viral hepatitis is a major public health concern in Brazil. There are few past studies on this issue, especially among riparian communities. This study aims at determining the seroprevalence of viral hepatitis B and C in the riparian community of Pacuí Island, within the Cametá municipality of Pará State, Brazil. Moreover, this study aims to investigate the principal risk factors that this community is exposed to.
METHODS: The current study has accessed blood samples from 181 volunteers who have answered an epidemiological questionnaire. Analyses on serological markers have been tested with commercial ELISA kits for detecting HBsAg, total anti-HBc, anti-HBs, and anti-HCV. Within seroreactive patients for HCV, RT-PCR and line probe assay have been performed to identify the viral genotype.
RESULTS: In the serological marker analysis for hepatitis B, no reactivity for HBsAg, rate of 1.1% for total anti-HBc, and rate of 19.3% for anti-HBs have been observed. On hepatitis C, 8.8% seroprevalence has been found, in which 62.5% have gotten viral RNA. Among the risk factors studied, the following have been highlighted: non-use of condoms, sharing of cutting instruments, use of illicit drugs, and reports of family disease with HBV or HCV.
CONCLUSIONS: The vaccination coverage against HBV is low, and the high prevalence of HCV within this community has been observed. |
| format |
Artigo |
| author |
OLIVEIRA, Claudia Suellen Ferro de |
| author2 |
SILVA, Adenielson Vilar e SANTOS, Kemper Nunes dos FECURY, Amanda Alves ALMEIDA, Marcella Kelly Costa de FERNANDES, Adriana Prado COSTA, Carlos Araújo da FREITAS, Andrei Silva CORVELO, Tereza Cristina de Oliveira MARTINS, Luisa Caricio |
| author2Str |
SILVA, Adenielson Vilar e SANTOS, Kemper Nunes dos FECURY, Amanda Alves ALMEIDA, Marcella Kelly Costa de FERNANDES, Adriana Prado COSTA, Carlos Araújo da FREITAS, Andrei Silva CORVELO, Tereza Cristina de Oliveira MARTINS, Luisa Caricio |
| title |
Hepatitis B and C virus infection among Brazilian Amazon riparians |
| title_short |
Hepatitis B and C virus infection among Brazilian Amazon riparians |
| title_full |
Hepatitis B and C virus infection among Brazilian Amazon riparians |
| title_fullStr |
Hepatitis B and C virus infection among Brazilian Amazon riparians |
| title_full_unstemmed |
Hepatitis B and C virus infection among Brazilian Amazon riparians |
| title_sort |
hepatitis b and c virus infection among brazilian amazon riparians |
| publishDate |
2014 |
| url |
http://repositorio.ufpa.br/jspui/handle/2011/6162 |
| _version_ |
1832603208725299200 |
| score |
11.755432 |