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Artigo
Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil
Human Bocavirus (HBoV) is a recently discovered virus and was first detected in the nasopharyngeal aspirate samples and after in stool samples, suggesting that HBoV may be a causative agent for human enteric infections. Due to absence of treatment options, there is a need to understand the diseas...
Autor principal: | Soares, Luana da Silva |
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Outros Autores: | Lima, A. B, Pantoja, K. C, Lobo, Patr?cia dos Santos, Cruz, J. F, Guerra, Sylvia de F?tima dos Santos, Bezerra, D. A. M, Bandeira, R. S, Mascarenhas, Joana D'Arc Pereira |
Grau: | Artigo |
Idioma: | eng |
Publicado em: |
Cold Spring Harbor Laboratory
2019
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Acesso em linha: |
http://patua.iec.gov.br//handle/iec/3639 |
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ir-iec-36392019-09-10T18:19:06Z Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil Soares, Luana da Silva Lima, A. B Pantoja, K. C Lobo, Patr?cia dos Santos Cruz, J. F Guerra, Sylvia de F?tima dos Santos Bezerra, D. A. M Bandeira, R. S Mascarenhas, Joana D'Arc Pereira Bocavirus Humano / patogenicidade Infec??es por Parvoviridae / virologia Gastroenterite / virologia Human Bocavirus (HBoV) is a recently discovered virus and was first detected in the nasopharyngeal aspirate samples and after in stool samples, suggesting that HBoV may be a causative agent for human enteric infections. Due to absence of treatment options, there is a need to understand the disease-causing mechanism of these viruses. The aim of this was to demonstrate the prevalence of HBoV from children less than 10 years with acute gastroenteritis in Brazil, during November 2011 to November 2012. Stool samples from hospitalized children ? 10 years who presented symptoms of acute gastroenteritis were analyzed for the presence of HBoV DNA by nested-PCR. HBoVpositivity was detected in 24.0% (54/225) of samples. Two peaks of HBoV detection were observed, during November 2011 and July to September 2012. Co-infections between HBoV and rotavirus A were identified in 50.0% (27/54) of specimens. Phylogenetic analysis identified the presence of HBoV-1 (94.8%), HBoV-2 (2.6%) and HBoV-3 (2.6%) species, with only minor variations among them. Further investigations are necessary to improve the knowledge on the role of HBoV in gastrointestinal infections. 2019-04-12T12:23:09Z 2019-04-12T12:23:09Z 2018 Artigo SOARES, Luana da Silva et al. Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil. bioRxiv, e404632, p. 1-17, 2018. http://patua.iec.gov.br//handle/iec/3639 10.1101/404632 eng Acesso Aberto application/pdf Cold Spring Harbor Laboratory |
institution |
Instituto Evandro Chagas (IEC) |
collection |
PATUA |
language |
eng |
topic |
Bocavirus Humano / patogenicidade Infec??es por Parvoviridae / virologia Gastroenterite / virologia |
spellingShingle |
Bocavirus Humano / patogenicidade Infec??es por Parvoviridae / virologia Gastroenterite / virologia Soares, Luana da Silva Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil |
topic_facet |
Bocavirus Humano / patogenicidade Infec??es por Parvoviridae / virologia Gastroenterite / virologia |
description |
Human Bocavirus (HBoV) is a recently discovered virus and was first detected in the
nasopharyngeal aspirate samples and after in stool samples, suggesting that HBoV may
be a causative agent for human enteric infections. Due to absence of treatment options,
there is a need to understand the disease-causing mechanism of these viruses. The aim
of this was to demonstrate the prevalence of HBoV from children less than 10 years
with acute gastroenteritis in Brazil, during November 2011 to November 2012. Stool
samples from hospitalized children ? 10 years who presented symptoms of acute
gastroenteritis were analyzed for the presence of HBoV DNA by nested-PCR. HBoVpositivity was detected in 24.0% (54/225) of samples. Two peaks of HBoV detection
were observed, during November 2011 and July to September 2012. Co-infections
between HBoV and rotavirus A were identified in 50.0% (27/54) of specimens.
Phylogenetic analysis identified the presence of HBoV-1 (94.8%), HBoV-2 (2.6%) and
HBoV-3 (2.6%) species, with only minor variations among them. Further investigations
are necessary to improve the knowledge on the role of HBoV in gastrointestinal
infections. |
format |
Artigo |
author |
Soares, Luana da Silva |
author2 |
Lima, A. B Pantoja, K. C Lobo, Patr?cia dos Santos Cruz, J. F Guerra, Sylvia de F?tima dos Santos Bezerra, D. A. M Bandeira, R. S Mascarenhas, Joana D'Arc Pereira |
author2Str |
Lima, A. B Pantoja, K. C Lobo, Patr?cia dos Santos Cruz, J. F Guerra, Sylvia de F?tima dos Santos Bezerra, D. A. M Bandeira, R. S Mascarenhas, Joana D'Arc Pereira |
title |
Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil |
title_short |
Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil |
title_full |
Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil |
title_fullStr |
Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil |
title_full_unstemmed |
Detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from Brazil |
title_sort |
detection and molecular epidemiology of human bocavirus in children with acute gastroenteritis from brazil |
publisher |
Cold Spring Harbor Laboratory |
publishDate |
2019 |
url |
http://patua.iec.gov.br//handle/iec/3639 |
_version_ |
1717584375982325760 |
score |
11.653393 |